Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 1886..2913 Replicon plasmid pSU3
Accession NZ_CP021747
Organism Agarilytica rhodophyticola strain 017

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag BVC89_RS29260 Protein ID WP_103654485.1
Coordinates 2341..2913 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag BVC89_RS29255 Protein ID WP_103654484.1
Coordinates 1886..2344 (+) Length 153 a.a.

Genomic Context

BVC89_RS29240BVC89_RS29245BVC89_RS29255BVC89_RS29260BVC89_RS29265BVC89_RS29270BVC89_RS29275BVC89_RS29280BVC89_RS29285BVC89_RS29290BVC89_RS29295BVC89_RS29300
Location: 115..465 (351 bp)
Type: Others
Protein ID: WP_103654482.1
Location: 795..1529 (735 bp)
Type: Others
Protein ID: WP_103654526.1
Location: 1886..2344 (459 bp)
Type: Antitoxin
Protein ID: WP_103654484.1
Location: 2341..2913 (573 bp)
Type: Toxin
Protein ID: WP_103654485.1
Location: 3129..3578 (450 bp)
Type: Others
Protein ID: WP_158658206.1
Location: 3590..4552 (963 bp)
Type: Others
Protein ID: WP_103654486.1
Location: 4671..4949 (279 bp)
Type: Others
Protein ID: WP_103654487.1
Location: 4972..5190 (219 bp)
Type: Others
Protein ID: WP_103654488.1
Location: 5198..5785 (588 bp)
Type: Others
Protein ID: WP_103654489.1
Location: 5808..6422 (615 bp)
Type: Others
Protein ID: WP_103654490.1
Location: 6540..7142 (603 bp)
Type: Others
Protein ID: WP_103654491.1
Location: 7146..7727 (582 bp)
Type: Others
Protein ID: WP_103654492.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BVC89_RS29240115..465+351WP_103654482.1hypothetical protein-
BVC89_RS29245795..1529+735WP_103654526.1SprT-like domain-containing protein-
BVC89_RS292551886..2344+459WP_103654484.1excisionase family DNA-binding proteinAntitoxin
BVC89_RS292602341..2913+573WP_103654485.1PIN domain-containing proteinToxin
BVC89_RS292653129..3578+450WP_158658206.1YkgJ family cysteine cluster protein-
BVC89_RS292703590..4552+963WP_103654486.1hypothetical protein-
BVC89_RS292754671..4949+279WP_103654487.1DUF1778 domain-containing protein-
BVC89_RS292804972..5190-219WP_103654488.1hypothetical protein-
BVC89_RS292855198..5785-588WP_103654489.1hypothetical protein-
BVC89_RS292905808..6422-615WP_103654490.1hypothetical protein-
BVC89_RS292956540..7142-603WP_103654491.1hypothetical protein-
BVC89_RS293007146..7727-582WP_103654492.1AHH domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..3152731527


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-114)

Antitoxin

Helix-turn-helix domain, group 17

(81-125)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21783.33 Da        Isoelectric Point: 6.7483

>T77280 WP_103654485.1 NZ_CP021747:2341-2913 [Agarilytica rhodophyticola]
MTSNFTVVYDACVMYPAPLRSFLMYLALTDMFRARWSDMIHDEWIRNLLANRPDLTQKQLTRTKDLMNANVRGCLVSGFE
PLIEAVELPDPDDRHVVAAAIHTRAEAIVTFNLKDFPDRALDKFNLKAIHPDEFIMDLMDLHIGTVIEAARTHRQSLKNP
PFTADAYLDCLLKQQLPQSVSRLRALKVML

Download         Length: 573 bp

>T77280 NZ_CP021747:2341-2913 [Agarilytica rhodophyticola]
ATGACTTCCAATTTCACAGTTGTCTATGATGCATGCGTGATGTATCCCGCCCCATTGCGGAGCTTTCTTATGTACCTAGC
TTTGACGGATATGTTCAGAGCTAGGTGGTCGGATATGATCCATGATGAATGGATCCGTAACTTACTAGCAAATCGGCCAG
ATTTAACTCAGAAACAGCTTACTCGCACGAAAGACCTAATGAATGCCAACGTTAGGGGATGTTTAGTTTCCGGGTTTGAG
CCGCTTATAGAAGCCGTTGAGCTTCCCGATCCAGACGACCGCCATGTGGTGGCCGCCGCAATACATACGCGCGCAGAAGC
GATCGTAACGTTTAATTTAAAGGACTTCCCAGACCGCGCACTAGATAAATTCAATTTAAAGGCTATTCACCCAGACGAAT
TCATCATGGATTTAATGGATCTCCATATCGGTACCGTGATCGAGGCAGCCAGAACACACCGCCAAAGCTTAAAGAACCCG
CCTTTTACGGCAGATGCTTACCTAGATTGCCTACTCAAACAACAGTTGCCACAAAGTGTTTCTCGGCTAAGAGCACTTAA
AGTAATGCTATAA

Antitoxin


Download         Length: 153 a.a.        Molecular weight: 16849.25 Da        Isoelectric Point: 5.0288

>AT77280 WP_103654484.1 NZ_CP021747:1886-2344 [Agarilytica rhodophyticola]
MNLLQEKLPTPEEAALAKLSSRELSAFLETKADSQAVSITDKEGIAHAVEIPVSALRLLVEVLTQLGEGNTVNLIPVHAQ
LTTQEGADILNVSRPTFIKLLDDEKIPYHRVGNRRKVAFSDVLNYKHDIDKKRLASLSELSELDQAMNMGYE

Download         Length: 459 bp

>AT77280 NZ_CP021747:1886-2344 [Agarilytica rhodophyticola]
ATGAACCTCCTACAAGAAAAGCTACCTACACCAGAAGAAGCAGCACTGGCAAAACTGTCCAGCCGCGAGTTGTCTGCTTT
CTTGGAGACAAAAGCAGACTCACAAGCCGTAAGCATCACCGATAAAGAGGGTATCGCGCACGCAGTCGAAATTCCTGTTA
GCGCTCTCCGTCTCCTGGTTGAAGTATTAACACAACTTGGAGAAGGTAATACGGTTAACCTTATACCCGTCCATGCTCAG
CTTACAACTCAAGAGGGTGCCGACATACTTAACGTATCTCGACCCACGTTTATAAAGCTACTGGATGATGAAAAAATTCC
TTATCATCGTGTCGGTAACAGGCGTAAAGTCGCCTTTTCTGATGTGCTGAACTACAAGCATGACATCGATAAGAAGCGCC
TAGCGTCGCTCTCTGAGCTCTCTGAGCTCGACCAAGCAATGAATATGGGATACGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
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References