Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4010176..4010321 | Replicon | chromosome |
| Accession | NZ_CP021740 | ||
| Organism | Klebsiella pneumoniae strain AR_0126 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4010183..4010285 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4010176..4010321 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AM373_RS20110 | 4005708..4007141 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| AM373_RS20115 | 4007257..4007496 | + | 240 | WP_002911393.1 | YebV family protein | - |
| AM373_RS20120 | 4007594..4007785 | + | 192 | WP_002911395.1 | YebW family protein | - |
| AM373_RS20125 | 4007782..4008435 | - | 654 | WP_009484457.1 | protein-serine/threonine phosphatase | - |
| AM373_RS20130 | 4008592..4009560 | + | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| AM373_RS28495 | 4009665..4009808 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 4010176..4010321 | + | 146 | - | - | Antitoxin |
| - | 4010183..4010285 | - | 103 | - | - | Toxin |
| AM373_RS20140 | 4010444..4010782 | - | 339 | WP_002911404.1 | YebY family protein | - |
| AM373_RS20145 | 4010799..4011668 | - | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| AM373_RS20150 | 4011672..4012046 | - | 375 | WP_020316569.1 | CopC domain-containing protein YobA | - |
| AM373_RS20155 | 4012159..4012389 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| AM373_RS20160 | 4012468..4013127 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| AM373_RS20165 | 4013131..4015191 | - | 2061 | WP_032419805.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T77270 NZ_CP021740:c4010285-4010183 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT77270 NZ_CP021740:4010176-4010321 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT