Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4010176..4010321 Replicon chromosome
Accession NZ_CP021740
Organism Klebsiella pneumoniae strain AR_0126

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4010183..4010285 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4010176..4010321 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM373_RS20110 4005708..4007141 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM373_RS20115 4007257..4007496 + 240 WP_002911393.1 YebV family protein -
AM373_RS20120 4007594..4007785 + 192 WP_002911395.1 YebW family protein -
AM373_RS20125 4007782..4008435 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
AM373_RS20130 4008592..4009560 + 969 WP_014907334.1 VirK/YbjX family protein -
AM373_RS28495 4009665..4009808 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4010176..4010321 + 146 - - Antitoxin
- 4010183..4010285 - 103 - - Toxin
AM373_RS20140 4010444..4010782 - 339 WP_002911404.1 YebY family protein -
AM373_RS20145 4010799..4011668 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
AM373_RS20150 4011672..4012046 - 375 WP_020316569.1 CopC domain-containing protein YobA -
AM373_RS20155 4012159..4012389 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM373_RS20160 4012468..4013127 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM373_RS20165 4013131..4015191 - 2061 WP_032419805.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T77270 NZ_CP021740:c4010285-4010183 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT77270 NZ_CP021740:4010176-4010321 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References