Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 818273..818418 Replicon chromosome
Accession NZ_CP021708
Organism Klebsiella pneumoniae strain AR_0143

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 818309..818411 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 818273..818418 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM390_RS04110 813403..815463 + 2061 WP_004151449.1 oligopeptidase B -
AM390_RS04115 815467..816126 - 660 WP_043906809.1 exodeoxyribonuclease X -
AM390_RS04120 816205..816435 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AM390_RS04125 816548..816922 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AM390_RS04130 816926..817795 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
AM390_RS04135 817812..818150 + 339 WP_002911404.1 YebY family protein -
- 818273..818418 - 146 - - Antitoxin
- 818309..818411 + 103 - - Toxin
AM390_RS30485 818787..818930 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AM390_RS04145 819035..820003 - 969 WP_004151446.1 VirK/YbjX family protein -
AM390_RS04150 820160..820813 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
AM390_RS04155 820810..821001 - 192 WP_002911395.1 YebW family protein -
AM390_RS04160 821099..821338 - 240 WP_002911393.1 YebV family protein -
AM390_RS04165 821454..822887 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T77080 NZ_CP021708:818309-818411 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT77080 NZ_CP021708:c818418-818273 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References