Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1766921..1767066 Replicon chromosome
Accession NZ_CP021696
Organism Klebsiella pneumoniae strain AR_0158

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1766928..1767030 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1766921..1767066 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM404_RS09045 1762453..1763886 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM404_RS09050 1764002..1764241 + 240 WP_002911393.1 YebV family protein -
AM404_RS09055 1764339..1764530 + 192 WP_002911395.1 YebW family protein -
AM404_RS09060 1764527..1765180 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
AM404_RS09065 1765337..1766305 + 969 WP_073972692.1 DUF535 family protein -
AM404_RS29510 1766410..1766553 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1766921..1767066 + 146 - - Antitoxin
- 1766928..1767030 - 103 - - Toxin
AM404_RS09075 1767189..1767527 - 339 WP_061891631.1 YebY family protein -
AM404_RS09080 1767544..1768413 - 870 WP_023282759.1 copper homeostasis membrane protein CopD -
AM404_RS09085 1768417..1768791 - 375 WP_004151448.1 CopC domain-containing protein YobA -
AM404_RS09090 1768904..1769134 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM404_RS09095 1769213..1769872 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM404_RS09100 1769876..1771936 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T77053 NZ_CP021696:c1767030-1766928 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT77053 NZ_CP021696:1766921-1767066 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References