Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1367589..1368123 Replicon chromosome
Accession NZ_CP021659
Organism Candidatus Fukatsuia symbiotica strain 5D

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CCS41_RS06930 Protein ID WP_119797427.1
Coordinates 1367589..1367879 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CCS41_RS06935 Protein ID WP_119797428.1
Coordinates 1367869..1368123 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCS41_RS06905 1362938..1363761 + 824 Protein_1342 IS5 family transposase -
CCS41_RS16070 1364139..1364417 - 279 WP_205411510.1 hypothetical protein -
CCS41_RS06915 1364686..1364991 - 306 WP_119797425.1 hypothetical protein -
CCS41_RS06920 1364985..1366112 - 1128 WP_119797426.1 recombinase family protein -
CCS41_RS06925 1366288..1366953 + 666 WP_119797736.1 DUF917 domain-containing protein -
CCS41_RS06930 1367589..1367879 - 291 WP_119797427.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CCS41_RS06935 1367869..1368123 - 255 WP_119797428.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CCS41_RS06940 1368322..1368944 + 623 Protein_1349 recombinase family protein -
CCS41_RS06945 1368986..1369399 + 414 WP_119797429.1 hypothetical protein -
CCS41_RS06950 1369363..1372206 + 2844 WP_162860022.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11403.42 Da        Isoelectric Point: 8.2565

>T76909 WP_119797427.1 NZ_CP021659:c1367879-1367589 [Candidatus Fukatsuia symbiotica]
MIFNIDFDERALKEWLKLDKAICEQFKKKLRKLQENPYIESACLHGDLAGCFKIKLRSSEFRLIYQVIDEEIVILVLAVG
KREDEKVYDVARKRIQ

Download         Length: 291 bp

>T76909 NZ_CP021659:c1367879-1367589 [Candidatus Fukatsuia symbiotica]
ATGATCTTTAATATCGACTTTGACGAACGGGCGTTAAAGGAGTGGCTGAAGCTCGATAAAGCCATTTGTGAGCAGTTTAA
AAAAAAGCTGCGGAAGCTACAGGAAAATCCTTACATTGAATCTGCATGTTTACACGGAGATCTGGCAGGTTGTTTTAAAA
TCAAGCTACGCTCCTCGGAATTTCGTCTAATTTATCAGGTGATTGATGAAGAGATTGTGATTTTGGTTCTTGCCGTTGGC
AAGCGGGAAGACGAAAAAGTCTATGATGTAGCCCGTAAGCGGATTCAATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9853.20 Da        Isoelectric Point: 4.4569

>AT76909 WP_119797428.1 NZ_CP021659:c1368123-1367869 [Candidatus Fukatsuia symbiotica]
MSTIQIRVDEELKKNAYQTFEKLNLSPSDALRLFLRYVAENEKLPFSEVSVMVSEEDEDADILEVVRERLKNPARRIRVN
LDDL

Download         Length: 255 bp

>AT76909 NZ_CP021659:c1368123-1367869 [Candidatus Fukatsuia symbiotica]
ATGAGTACCATTCAGATCCGTGTGGATGAAGAGCTGAAAAAAAATGCGTATCAGACATTTGAAAAACTGAATTTGTCACC
GTCTGATGCCCTGCGCCTGTTTTTGCGCTATGTCGCAGAGAATGAAAAGCTGCCATTTTCTGAGGTATCCGTGATGGTAA
GTGAAGAAGATGAAGACGCTGATATTCTGGAGGTAGTCCGTGAACGCCTGAAAAACCCCGCCAGACGTATCAGGGTAAAC
CTTGATGATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References