Detailed information of TA system TA076908

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): chpSB/PRK09812-ChpS
• Location: 1312907..1313508
• Replicon: chromosome
• Accession: NZ_CP021659
• Organism: Candidatus Fukatsuia symbiotica strain 5D

Toxin (Protein)

• Gene name: chpB
• Uniprot ID: -
• Locus tag: CCS41_RS06630
• Protein ID: WP_162860101.1
• Coordinates: 1313158..1313508 (+)
• Length: 117 a.a.

Antitoxin (Protein)

• Gene name: chpS
• Uniprot ID: -
• Locus tag: CCS41_RS06625
• Protein ID: WP_119797406.1
• Coordinates: 1312907..1313161 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CCS41_RS06590	1308004..1309145	+	1142	Protein_1285	P22 coat - protein 5 family protein	-
CCS41_RS06595	1309266..1310288	+	1023	WP_119797384.1	IS630 family transposase	-
CCS41_RS15625	1310754..1310924	+	171	WP_162859964.1	hypothetical protein	-
CCS41_RS06605	1310869..1311405	+	537	WP_205411504.1	hypothetical protein	-
CCS41_RS06610	1311410..1311748	+	339	WP_119797404.1	hypothetical protein	-
CCS41_RS06615	1311905..1312360	+	456	WP_119797405.1	hypothetical protein	-
CCS41_RS06620	1312357..1312763	+	407	Protein_1291	hypothetical protein	-
CCS41_RS06625	1312907..1313161	+	255	WP_119797406.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
CCS41_RS06630	1313158..1313508	+	351	WP_162860101.1	type II toxin-antitoxin system ChpB family toxin	Toxin
CCS41_RS06635	1313615..1314276	+	662	Protein_1294	phage tail protein	-
CCS41_RS06640	1314288..1314599	+	312	WP_119797408.1	hypothetical protein	-
CCS41_RS06645	1314596..1314811	+	216	WP_119797409.1	DUF1799 domain-containing protein	-
CCS41_RS06650	1314813..1315217	-	405	Protein_1297	transposase	-
CCS41_RS06655	1315270..1315638	-	369	WP_119797707.1	IS630 transposase-related protein	-
CCS41_RS06660	1315794..1318367	+	2574	WP_119797410.1	phage tail tape measure protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1293638..1332207	38569

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (7-114)

Antitoxin

• Antitoxin PemI-like (1-84)

Sequences

Toxin

Protein

• Length: 117 a.a.
• Molecular weight: 12731.66 Da
• Isoelectric Point: 9.9203

>T76908 WP_162860101.1 NZ_CP021659:1313158-1313508 [Candidatus Fukatsuia symbiotica]
VTRRKGFSRGDIVLLTLNPTRGKEQQGDRRPVLVLSPKNFNDLGMVLIAPITQGGAFSRYQGFTVTLSGSGAQTQGVVLL
NQSRMVDITARDGEFIEKADHIVIEEALIKLHTLIE

Nucleotide

• Length: 351 bp

>T76908 NZ_CP021659:1313158-1313508 [Candidatus Fukatsuia symbiotica]
GTGACACGTAGAAAAGGATTTTCGCGCGGTGATATCGTATTGTTAACACTCAACCCGACTCGAGGAAAAGAACAGCAAGG
TGACAGACGACCAGTATTGGTACTCTCTCCTAAAAACTTCAATGATCTTGGCATGGTTTTGATTGCCCCGATCACACAAG
GCGGTGCTTTCTCAAGGTATCAGGGTTTCACGGTAACATTATCAGGGAGTGGCGCGCAAACCCAAGGCGTCGTGTTATTA
AATCAAAGCAGAATGGTTGATATCACTGCCCGAGACGGTGAATTCATTGAAAAAGCTGATCACATCGTGATTGAAGAAGC
GCTCATTAAACTACACACCCTCATCGAATAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9218.63 Da
• Isoelectric Point: 4.5680

>AT76908 WP_119797406.1 NZ_CP021659:1312907-1313161 [Candidatus Fukatsuia symbiotica]
MTVAIKKWGNSNGIVIPALFLKKIGVSVGQELDLEIKDGTLVLTPKPKRYTLAELIKQCDASAPLETEESVWGDDHSPVG
EEIW

Nucleotide

• Length: 255 bp

>AT76908 NZ_CP021659:1312907-1313161 [Candidatus Fukatsuia symbiotica]
ATGACAGTAGCCATCAAAAAATGGGGCAATAGCAACGGTATCGTCATACCGGCGCTCTTTCTGAAAAAAATTGGGGTCTC
TGTAGGTCAAGAACTGGATCTGGAAATCAAAGACGGCACCTTGGTTCTGACGCCCAAACCTAAGCGTTACACCCTGGCCG
AACTGATTAAACAATGTGATGCCAGTGCCCCACTTGAAACGGAAGAAAGTGTATGGGGTGACGATCACTCCCCCGTAGGG
GAAGAAATATGGTGA