Detailed information of TA system TA076903

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-DnaT
• Location: 324816..325338
• Replicon: chromosome
• Accession: NZ_CP021659
• Organism: Candidatus Fukatsuia symbiotica strain 5D

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CCS41_RS01595
• Protein ID: WP_119797051.1
• Coordinates: 324816..325097 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CCS41_RS01600
• Protein ID: WP_119797052.1
• Coordinates: 325087..325338 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CCS41_RS01580	320609..321424	-	816	WP_119797048.1	GPO family capsid scaffolding protein	-
CCS41_RS01585	321590..323383	+	1794	WP_119797049.1	terminase family protein	-
CCS41_RS01590	323383..324387	+	1005	WP_119797050.1	phage portal protein	-
CCS41_RS01595	324816..325097	-	282	WP_119797051.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CCS41_RS01600	325087..325338	-	252	WP_119797052.1	plasmid stabilization protein	Antitoxin
CCS41_RS01605	325545..327632	-	2088	WP_119797053.1	replication endonuclease	-
CCS41_RS01610	328114..328461	-	348	WP_119797054.1	DUF5347 family protein	-
CCS41_RS01615	328403..328690	-	288	WP_162859944.1	DUF2724 domain-containing protein	-
CCS41_RS01625	329324..329680	-	357	WP_119797056.1	hypothetical protein	-
CCS41_RS01630	329677..330027	-	351	WP_119797057.1	hypothetical protein	-
CCS41_RS01635	330089..330313	+	225	WP_119797058.1	helix-turn-helix domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	310569..332338	21769

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10823.56 Da
• Isoelectric Point: 10.5388

>T76903 WP_119797051.1 NZ_CP021659:c325097-324816 [Candidatus Fukatsuia symbiotica]
MIYKLKFEKRALKEWDKLGHTLKQQLKNKLSERLDNPHIPSARLSGKTNRYKIKLRASGYRLVYEVNDSDVVLLVIAIGK
RAGDDIYHSADQR

Nucleotide

• Length: 282 bp

>T76903 NZ_CP021659:c325097-324816 [Candidatus Fukatsuia symbiotica]
ATGATTTATAAGTTAAAATTTGAAAAACGCGCTTTAAAAGAATGGGATAAATTAGGTCATACACTGAAACAACAGTTAAA
AAATAAGCTGTCTGAAAGGTTGGACAATCCGCATATTCCATCAGCAAGGTTAAGTGGGAAGACTAATCGCTATAAAATTA
AATTAAGAGCGTCTGGTTACAGATTAGTCTACGAAGTTAATGATAGCGACGTCGTTTTACTTGTGATCGCTATAGGAAAA
AGAGCAGGGGATGACATTTATCACTCTGCTGATCAACGTTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9242.45 Da
• Isoelectric Point: 4.0470

>AT76903 WP_119797052.1 NZ_CP021659:c325338-325087 [Candidatus Fukatsuia symbiotica]
MAHQILAEMAASITDLKRNPMGTVADAEGEAIAILNRNQPAFYCVPPKLYAYYQELAEDAELNRIADERMANPEFVSVNL
DDL

Nucleotide

• Length: 252 bp

>AT76903 NZ_CP021659:c325338-325087 [Candidatus Fukatsuia symbiotica]
ATGGCTCATCAAATCCTAGCGGAAATGGCTGCCAGTATTACCGATCTCAAACGTAACCCTATGGGTACGGTTGCAGACGC
TGAGGGTGAGGCCATCGCTATCCTTAATCGTAATCAACCCGCTTTTTATTGTGTACCGCCTAAACTTTATGCTTACTATC
AGGAACTCGCCGAAGATGCTGAGCTTAACCGTATCGCTGATGAGCGAATGGCAAACCCCGAGTTTGTGAGCGTAAATCTA
GATGATTTATAA