76811

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3858481..3858626 Replicon chromosome
Accession NZ_CP021539
Organism Klebsiella pneumoniae strain AR_0047

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3858488..3858590 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3858481..3858626 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM426_RS19480 3854013..3855446 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM426_RS19485 3855562..3855801 + 240 WP_002911393.1 YebV family protein -
AM426_RS19490 3855899..3856090 + 192 WP_002911395.1 YebW family protein -
AM426_RS19495 3856087..3856740 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
AM426_RS19500 3856897..3857865 + 969 WP_004151446.1 VirK/YbjX family protein -
AM426_RS29905 3857970..3858113 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3858481..3858626 + 146 - - Antitoxin
- 3858488..3858590 - 103 - - Toxin
AM426_RS19510 3858749..3859087 - 339 WP_002911404.1 YebY family protein -
AM426_RS19515 3859104..3859973 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
AM426_RS19520 3859977..3860351 - 375 WP_004151448.1 CopC domain-containing protein YobA -
AM426_RS19525 3860464..3860694 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM426_RS19530 3860773..3861432 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM426_RS19535 3861436..3863496 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T76811 NZ_CP021539:c3858590-3858488 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT76811 NZ_CP021539:3858481-3858626 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References