Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 313861..314390 Replicon plasmid pAP1447-1
Accession NZ_CP021525
Organism Acetobacter ascendens strain SRCM101447

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag S101447_RS15160 Protein ID WP_087636598.1
Coordinates 314100..314390 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag S101447_RS15155 Protein ID WP_087636597.1
Coordinates 313861..314103 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
S101447_RS15135 309657..311582 + 1926 WP_087636595.1 hypothetical protein -
S101447_RS15140 311585..311821 + 237 WP_003627225.1 exodeoxyribonuclease VII small subunit -
S101447_RS15145 311784..312377 - 594 WP_157894007.1 hypothetical protein -
S101447_RS15150 312420..313504 - 1085 Protein_320 IS3 family transposase -
S101447_RS15155 313861..314103 + 243 WP_087636597.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
S101447_RS15160 314100..314390 + 291 WP_087636598.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
S101447_RS15165 314393..315478 + 1086 WP_087636599.1 hypothetical protein -
S101447_RS15170 315491..316537 - 1047 WP_087636600.1 Fic family protein -
S101447_RS15175 316534..316890 - 357 WP_193562012.1 hypothetical protein -
S101447_RS15180 316982..318276 - 1295 Protein_326 replication protein C -
S101447_RS15190 319046..319324 - 279 WP_019088706.1 DUF2312 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..336151 336151


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10942.62 Da        Isoelectric Point: 9.6563

>T76732 WP_087636598.1 NZ_CP021525:314100-314390 [Acetobacter ascendens]
VSRYALHFDPRAKREWDSLDGSIKILLKKALAKRLDEPHVSSAELSGDLRNCYKIKLRSSGYRLVYQMDDGKLIVLVIAI
GRRDAYEVYGDANCRA

Download         Length: 291 bp

>T76732 NZ_CP021525:314100-314390 [Acetobacter ascendens]
GTGAGTCGATACGCGCTGCATTTCGACCCACGCGCCAAACGCGAGTGGGATAGTCTTGATGGAAGCATCAAGATACTGCT
CAAGAAAGCGCTGGCCAAAAGATTGGACGAACCACATGTTTCGTCAGCCGAACTTTCCGGGGACTTACGGAACTGTTACA
AAATCAAGCTTCGCTCATCTGGGTATCGTCTGGTGTACCAAATGGACGATGGTAAGCTTATTGTATTAGTCATCGCTATC
GGCCGCAGGGATGCCTATGAGGTTTATGGCGATGCAAACTGCCGTGCCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8949.36 Da        Isoelectric Point: 5.0807

>AT76732 WP_087636597.1 NZ_CP021525:313861-314103 [Acetobacter ascendens]
MALINLRIDGSLKKAAYERLSELGVTPSDLIRQTFEYVVKTGKLPVRRTVISEEDQQLLAVVRERLASPEPSIPVSLDDL

Download         Length: 243 bp

>AT76732 NZ_CP021525:313861-314103 [Acetobacter ascendens]
ATGGCTTTAATTAACCTGCGTATTGATGGCAGCCTAAAGAAAGCTGCTTACGAGCGGCTCTCTGAACTTGGCGTGACACC
GTCAGATCTCATCCGCCAGACGTTTGAATATGTTGTGAAAACAGGCAAGCTTCCCGTTCGGCGTACAGTTATCTCAGAAG
AGGATCAGCAACTGCTGGCGGTTGTACGTGAACGTCTTGCCTCTCCCGAACCTTCTATTCCCGTCTCGCTGGATGATCTG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References