Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 313861..314390 Replicon plasmid pAP1447-1
Accession NZ_CP021525
Organism Acetobacter ascendens strain SRCM101447

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag S101447_RS15160 Protein ID WP_087636598.1
Coordinates 314100..314390 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag S101447_RS15155 Protein ID WP_087636597.1
Coordinates 313861..314103 (+) Length 81 a.a.

Genomic Context

S101447_RS15135S101447_RS15140S101447_RS15155S101447_RS15160S101447_RS15165S101447_RS15145S101447_RS15150S101447_RS15170S101447_RS15175S101447_RS15180S101447_RS15190
Location: 309657..311582 (1926 bp)
Type: Others
Protein ID: WP_087636595.1
Location: 311585..311821 (237 bp)
Type: Others
Protein ID: WP_003627225.1
Location: 313861..314103 (243 bp)
Type: Antitoxin
Protein ID: WP_087636597.1
Location: 314100..314390 (291 bp)
Type: Toxin
Protein ID: WP_087636598.1
Location: 314393..315478 (1086 bp)
Type: Others
Protein ID: WP_087636599.1
Location: 311784..312377 (594 bp)
Type: Others
Protein ID: WP_157894007.1
Location: 312420..313504 (1085 bp)
Type: Others
Protein ID: Protein_320
Location: 315491..316537 (1047 bp)
Type: Others
Protein ID: WP_087636600.1
Location: 316534..316890 (357 bp)
Type: Others
Protein ID: WP_193562012.1
Location: 316982..318276 (1295 bp)
Type: Others
Protein ID: Protein_326
Location: 319046..319324 (279 bp)
Type: Others
Protein ID: WP_019088706.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
S101447_RS15135309657..311582+1926WP_087636595.1hypothetical protein-
S101447_RS15140311585..311821+237WP_003627225.1exodeoxyribonuclease VII small subunit-
S101447_RS15145311784..312377-594WP_157894007.1hypothetical protein-
S101447_RS15150312420..313504-1085Protein_320IS3 family transposase-
S101447_RS15155313861..314103+243WP_087636597.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
S101447_RS15160314100..314390+291WP_087636598.1type II toxin-antitoxin system RelE/ParE family toxinToxin
S101447_RS15165314393..315478+1086WP_087636599.1hypothetical protein-
S101447_RS15170315491..316537-1047WP_087636600.1Fic family protein-
S101447_RS15175316534..316890-357WP_193562012.1hypothetical protein-
S101447_RS15180316982..318276-1295Protein_326replication protein C-
S101447_RS15190319046..319324-279WP_019088706.1DUF2312 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..336151336151


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10942.62 Da        Isoelectric Point: 9.6563

>T76732 WP_087636598.1 NZ_CP021525:314100-314390 [Acetobacter ascendens]
VSRYALHFDPRAKREWDSLDGSIKILLKKALAKRLDEPHVSSAELSGDLRNCYKIKLRSSGYRLVYQMDDGKLIVLVIAI
GRRDAYEVYGDANCRA

Download         Length: 291 bp

>T76732 NZ_CP021525:314100-314390 [Acetobacter ascendens]
GTGAGTCGATACGCGCTGCATTTCGACCCACGCGCCAAACGCGAGTGGGATAGTCTTGATGGAAGCATCAAGATACTGCT
CAAGAAAGCGCTGGCCAAAAGATTGGACGAACCACATGTTTCGTCAGCCGAACTTTCCGGGGACTTACGGAACTGTTACA
AAATCAAGCTTCGCTCATCTGGGTATCGTCTGGTGTACCAAATGGACGATGGTAAGCTTATTGTATTAGTCATCGCTATC
GGCCGCAGGGATGCCTATGAGGTTTATGGCGATGCAAACTGCCGTGCCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8949.36 Da        Isoelectric Point: 5.0807

>AT76732 WP_087636597.1 NZ_CP021525:313861-314103 [Acetobacter ascendens]
MALINLRIDGSLKKAAYERLSELGVTPSDLIRQTFEYVVKTGKLPVRRTVISEEDQQLLAVVRERLASPEPSIPVSLDDL

Download         Length: 243 bp

>AT76732 NZ_CP021525:313861-314103 [Acetobacter ascendens]
ATGGCTTTAATTAACCTGCGTATTGATGGCAGCCTAAAGAAAGCTGCTTACGAGCGGCTCTCTGAACTTGGCGTGACACC
GTCAGATCTCATCCGCCAGACGTTTGAATATGTTGTGAAAACAGGCAAGCTTCCCGTTCGGCGTACAGTTATCTCAGAAG
AGGATCAGCAACTGCTGGCGGTTGTACGTGAACGTCTTGCCTCTCCCGAACCTTCTATTCCCGTCTCGCTGGATGATCTG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References