Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-RelB |
| Location | 90350..90852 | Replicon | plasmid pAP1447-1 |
| Accession | NZ_CP021525 | ||
| Organism | Acetobacter ascendens strain SRCM101447 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | S101447_RS13965 | Protein ID | WP_087636510.1 |
| Coordinates | 90589..90852 (+) | Length | 88 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | S101447_RS13960 | Protein ID | WP_087636509.1 |
| Coordinates | 90350..90592 (+) | Length | 81 a.a. |
Genomic Context
Location: 86175..88163 (1989 bp)
Type: Others
Protein ID: WP_087636506.1
Type: Others
Protein ID: WP_087636506.1
Location: 90350..90592 (243 bp)
Type: Antitoxin
Protein ID: WP_087636509.1
Type: Antitoxin
Protein ID: WP_087636509.1
Location: 90589..90852 (264 bp)
Type: Toxin
Protein ID: WP_087636510.1
Type: Toxin
Protein ID: WP_087636510.1
Location: 90855..91940 (1086 bp)
Type: Others
Protein ID: WP_087636511.1
Type: Others
Protein ID: WP_087636511.1
Location: 88259..89191 (933 bp)
Type: Others
Protein ID: WP_157893998.1
Type: Others
Protein ID: WP_157893998.1
Location: 89570..90004 (435 bp)
Type: Others
Protein ID: WP_087636508.1
Type: Others
Protein ID: WP_087636508.1
Location: 92090..92647 (558 bp)
Type: Others
Protein ID: WP_087636512.1
Type: Others
Protein ID: WP_087636512.1
Location: 92650..93888 (1239 bp)
Type: Others
Protein ID: WP_087636610.1
Type: Others
Protein ID: WP_087636610.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| S101447_RS13945 | 86175..88163 | + | 1989 | WP_087636506.1 | HAD-IA family hydrolase | - |
| S101447_RS13950 | 88259..89191 | - | 933 | WP_157893998.1 | sulfotransferase | - |
| S101447_RS13955 | 89570..90004 | - | 435 | WP_087636508.1 | MucR family transcriptional regulator | - |
| S101447_RS13960 | 90350..90592 | + | 243 | WP_087636509.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| S101447_RS13965 | 90589..90852 | + | 264 | WP_087636510.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| S101447_RS13970 | 90855..91940 | + | 1086 | WP_087636511.1 | hypothetical protein | - |
| S101447_RS13975 | 92090..92647 | - | 558 | WP_087636512.1 | CdiI family contact-dependent growth inhibition immunity protein | - |
| S101447_RS13980 | 92650..93888 | - | 1239 | WP_087636610.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..336151 | 336151 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 88 a.a. Molecular weight: 10102.49 Da Isoelectric Point: 9.3723
>T76727 WP_087636510.1 NZ_CP021525:90589-90852 [Acetobacter ascendens]
MSRYALYFAPRAKREWGSLDGSIKRLDEPHVSSAEISRDLRDCYKIKLRSSGYRLVYQVDDGKLIVLVIALGRRDANEVY
DDTNHRI
MSRYALYFAPRAKREWGSLDGSIKRLDEPHVSSAEISRDLRDCYKIKLRSSGYRLVYQVDDGKLIVLVIALGRRDANEVY
DDTNHRI
Download Length: 264 bp
>T76727 NZ_CP021525:90589-90852 [Acetobacter ascendens]
TTGAGTCGATACGCGCTGTATTTCGCCCCACGCGCCAAACGCGAGTGGGGTAGTCTTGATGGAAGCATCAAGAGACTAGA
CGAACCACATGTTTCGTCAGCCGAAATTTCCAGGGACTTACGGGACTGTTACAAAATCAAGCTTCGCTCATCCGGGTATC
GTCTGGTGTACCAAGTGGACGATGGTAAGCTTATTGTATTAGTCATCGCTCTTGGCCGCAGGGATGCCAATGAAGTTTAT
GACGATACAAACCACCGTATCTGA
TTGAGTCGATACGCGCTGTATTTCGCCCCACGCGCCAAACGCGAGTGGGGTAGTCTTGATGGAAGCATCAAGAGACTAGA
CGAACCACATGTTTCGTCAGCCGAAATTTCCAGGGACTTACGGGACTGTTACAAAATCAAGCTTCGCTCATCCGGGTATC
GTCTGGTGTACCAAGTGGACGATGGTAAGCTTATTGTATTAGTCATCGCTCTTGGCCGCAGGGATGCCAATGAAGTTTAT
GACGATACAAACCACCGTATCTGA
Antitoxin
Download Length: 81 a.a. Molecular weight: 9011.35 Da Isoelectric Point: 4.7719
>AT76727 WP_087636509.1 NZ_CP021525:90350-90592 [Acetobacter ascendens]
MASINLRIDDSLKKAAYERLSELSVTPSDLIRQTFEYVVKTGKLPVRRTVISEEDQQLLAVVRERLASPEPSIPVSLDDL
MASINLRIDDSLKKAAYERLSELSVTPSDLIRQTFEYVVKTGKLPVRRTVISEEDQQLLAVVRERLASPEPSIPVSLDDL
Download Length: 243 bp
>AT76727 NZ_CP021525:90350-90592 [Acetobacter ascendens]
ATGGCTTCAATTAACCTGCGTATTGATGACAGCCTAAAGAAAGCTGCTTACGAGCGGCTCTCTGAACTTAGCGTGACACC
GTCAGATCTCATCCGCCAGACGTTTGAGTATGTTGTGAAAACAGGCAAGCTTCCCGTTCGGCGTACAGTTATATCAGAAG
AGGATCAGCAACTGCTGGCGGTTGTACGTGAACGTCTTGCCTCTCCCGAACCTTCTATTCCCGTCTCGCTGGATGATCTT
TGA
ATGGCTTCAATTAACCTGCGTATTGATGACAGCCTAAAGAAAGCTGCTTACGAGCGGCTCTCTGAACTTAGCGTGACACC
GTCAGATCTCATCCGCCAGACGTTTGAGTATGTTGTGAAAACAGGCAAGCTTCCCGTTCGGCGTACAGTTATATCAGAAG
AGGATCAGCAACTGCTGGCGGTTGTACGTGAACGTCTTGCCTCTCCCGAACCTTCTATTCCCGTCTCGCTGGATGATCTT
TGA