Detailed information of TA system TA076725

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): NpoTA/ParE(toxin)
• Location: 1929702..1930940
• Replicon: chromosome
• Accession: NZ_CP021524
• Organism: Acetobacter ascendens strain SRCM101447

Toxin (Protein)

• Gene name: NpoT
• Uniprot ID: -
• Locus tag: S101447_RS09270
• Protein ID: WP_087635931.1
• Coordinates: 1930638..1930940 (-)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: NpoA
• Uniprot ID: -
• Locus tag: S101447_RS09265
• Protein ID: WP_087635930.1
• Coordinates: 1929702..1930556 (-)
• Length: 285 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
S101447_RS09250	1925349..1926131	-	783	Protein_1781	SCO family protein	-
S101447_RS09255	1926193..1927662	+	1470	WP_087635928.1	FAD-dependent monooxygenase	-
S101447_RS09260	1927844..1929631	+	1788	WP_087635929.1	thiamine pyrophosphate-requiring protein	-
S101447_RS09265	1929702..1930556	-	855	WP_087635930.1	glucose 1-dehydrogenase	Antitoxin
S101447_RS09270	1930638..1930940	-	303	WP_087635931.1	plasmid stabilization protein	Toxin
S101447_RS09275	1931075..1933195	-	2121	WP_087635932.1	glycogen debranching protein GlgX	-
S101447_RS09280	1933425..1935053	+	1629	WP_087635933.1	glycogen synthase GlgA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 10852.82 Da
• Isoelectric Point: 10.8172

>T76725 WP_087635931.1 NZ_CP021524:c1930940-1930638 [Acetobacter ascendens]
MPRGDKSSYTDKQKRQAEHIEQNYEQHGVSEQEAERRAWATVNKETGGGKKSGSGRGHAVTHEPSRKGGKAGGEASAHRT
PEERSASARKAAATRKKNAK

Nucleotide

• Length: 303 bp

>T76725 NZ_CP021524:c1930940-1930638 [Acetobacter ascendens]
ATGCCTCGTGGTGACAAATCTTCTTACACAGACAAGCAAAAACGACAAGCCGAGCATATCGAACAAAACTACGAACAACA
TGGTGTAAGCGAACAGGAAGCTGAACGCCGAGCTTGGGCAACTGTCAACAAAGAAACGGGTGGTGGTAAGAAAAGTGGAT
CAGGAAGAGGCCATGCCGTAACGCATGAACCATCACGCAAAGGGGGCAAGGCTGGCGGAGAAGCTTCCGCGCATCGTACA
CCAGAAGAACGCTCTGCCTCAGCACGAAAAGCGGCTGCAACACGTAAGAAAAATGCAAAATAA

Antitoxin

Protein

• Length: 285 a.a.
• Molecular weight: 30370.43 Da
• Isoelectric Point: 4.9602

>AT76725 WP_087635930.1 NZ_CP021524:c1930556-1929702 [Acetobacter ascendens]
MMVHEEKIPPQNQTIPGETDQMNPVPDHGEKSYRGSGKLSGKVALITGADSGIGRAVAIAFAREGADIAIAYYTEDKDAQ
TTAEWVEKAGRRAILLPGDIQLQSHCNEIIKRTIDAFGQLDILVNNAAHQKSVTDISEINEEELDTTFRTNFYGLFFLCQ
AALPYLSSGASIINTTSINAVQPSPHLPVYAATKAAISNFTAGLAQMLGKKNIRVNAVAPGPVWTPLIPSTMPEEDIANF
GKNTPLGRPAQPAELASAYVMFASDEASYTTGAILPVTGGRPML

Nucleotide

• Length: 855 bp

>AT76725 NZ_CP021524:c1930556-1929702 [Acetobacter ascendens]
ATGATGGTACATGAAGAAAAAATTCCACCTCAAAATCAGACCATTCCGGGTGAAACAGACCAAATGAATCCTGTTCCAGA
TCATGGAGAAAAAAGTTATCGAGGGTCGGGAAAACTTTCTGGAAAAGTTGCTTTGATAACAGGAGCAGATTCAGGAATAG
GCCGAGCAGTTGCCATTGCTTTTGCGCGTGAAGGTGCAGATATCGCAATTGCTTATTATACAGAAGATAAAGATGCCCAA
ACCACAGCTGAATGGGTAGAAAAGGCCGGGCGCCGTGCTATTTTACTGCCGGGAGACATCCAGTTACAGTCACATTGTAA
CGAAATAATAAAACGTACAATTGATGCATTCGGGCAACTTGATATTCTGGTAAACAATGCAGCACACCAAAAGTCTGTAA
CAGATATTTCAGAAATTAATGAAGAAGAACTTGATACAACATTTCGCACAAATTTTTACGGGCTGTTCTTTCTATGTCAG
GCAGCCTTACCATATTTGAGCAGCGGTGCTTCCATTATCAACACAACTTCGATCAATGCTGTGCAGCCATCTCCTCACCT
GCCTGTTTATGCTGCCACAAAGGCAGCTATTTCCAACTTTACCGCGGGCCTTGCTCAAATGCTGGGCAAAAAAAACATAC
GCGTTAATGCTGTTGCACCTGGGCCTGTCTGGACACCTCTTATTCCATCTACAATGCCAGAAGAAGATATTGCCAATTTT
GGTAAAAATACACCTCTGGGGCGGCCTGCACAGCCAGCAGAGCTAGCTTCTGCCTACGTAATGTTCGCTTCTGATGAAGC
AAGTTATACAACAGGTGCCATTCTTCCTGTAACTGGAGGCAGGCCAATGCTTTGA