Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1918715..1919350 Replicon chromosome
Accession NZ_CP021524
Organism Acetobacter ascendens strain SRCM101447

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag S101447_RS09230 Protein ID WP_087635925.1
Coordinates 1918940..1919350 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID G2I1D7
Locus tag S101447_RS09225 Protein ID WP_010511771.1
Coordinates 1918715..1918939 (+) Length 75 a.a.

Genomic Context

S101447_RS09210S101447_RS09215S101447_RS09225S101447_RS09230S101447_RS09235S101447_RS09240S101447_RS15865S101447_RS09220
Location: 1915594..1916193 (600 bp)
Type: Others
Protein ID: WP_087635922.1
Location: 1916543..1918072 (1530 bp)
Type: Others
Protein ID: WP_162288301.1
Location: 1918715..1918939 (225 bp)
Type: Antitoxin
Protein ID: WP_010511771.1
Location: 1918940..1919350 (411 bp)
Type: Toxin
Protein ID: WP_087635925.1
Location: 1919783..1922440 (2658 bp)
Type: Others
Protein ID: WP_087635926.1
Location: 1922562..1922951 (390 bp)
Type: Others
Protein ID: WP_070323530.1
Location: 1914540..1914725 (186 bp)
Type: Others
Protein ID: WP_162288300.1
Location: 1918110..1918442 (333 bp)
Type: Others
Protein ID: WP_157893978.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
S101447_RS158651914540..1914725-186WP_162288300.1hypothetical protein-
S101447_RS092101915594..1916193+600WP_087635922.1hypothetical protein-
S101447_RS092151916543..1918072+1530WP_162288301.1recombinase family protein-
S101447_RS092201918110..1918442-333WP_157893978.1hypothetical protein-
S101447_RS092251918715..1918939+225WP_010511771.1hypothetical proteinAntitoxin
S101447_RS092301918940..1919350+411WP_087635925.1type II toxin-antitoxin system VapC family toxinToxin
S101447_RS092351919783..1922440+2658WP_087635926.1Hint domain-containing protein-
S101447_RS092401922562..1922951+390WP_070323530.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--1877870..191935041480


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(9-55)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15588.88 Da        Isoelectric Point: 6.4680

>T76724 WP_087635925.1 NZ_CP021524:1918940-1919350 [Acetobacter ascendens]
MLRYLLDTNLCIRVLRDRPQGLRPRFNSCAEELCISDVVLYELLYGAERSSDPVRTRREVERFAARLAVLPFDSEAAAHT
ADIRAELERNGRIIGPYDLMIAGHARSRGLIVVTGNLREFQRVEGLRTEDWLTDMV

Download         Length: 411 bp

>T76724 NZ_CP021524:1918940-1919350 [Acetobacter ascendens]
ATGTTGCGTTACCTGCTGGATACGAATCTCTGTATCCGGGTATTGCGGGATCGGCCGCAGGGGTTGCGTCCGAGATTCAA
CAGCTGTGCGGAGGAACTCTGCATCTCGGACGTGGTTCTGTATGAGCTGCTTTATGGCGCAGAACGCTCGTCCGATCCCG
TGCGCACAAGGCGTGAAGTCGAGCGCTTCGCGGCAAGGCTGGCGGTCCTGCCATTCGACAGTGAAGCAGCCGCCCATACG
GCAGACATTCGGGCCGAACTTGAACGGAATGGCCGTATCATAGGTCCGTATGATCTCATGATTGCCGGGCATGCCCGGAG
CAGAGGGCTGATTGTTGTGACCGGCAATCTGCGGGAATTTCAGCGGGTGGAGGGTCTTCGAACGGAGGACTGGCTGACTG
ACATGGTCTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8217.39 Da        Isoelectric Point: 4.9816

>AT76724 WP_010511771.1 NZ_CP021524:1918715-1918939 [Acetobacter ascendens]
MLTRTTLFLSNRSQAVRLPKMVAFGEQVRDVVIVSEGSRRIIAPADAAWDDFFAAPGVDLGERNQPAMQEREAL

Download         Length: 225 bp

>AT76724 NZ_CP021524:1918715-1918939 [Acetobacter ascendens]
ATGCTGACCCGTACGACACTCTTTCTATCCAACCGCTCGCAGGCAGTGCGTCTGCCGAAGATGGTCGCCTTCGGGGAACA
GGTGCGTGACGTCGTCATCGTGTCCGAAGGGTCGCGGCGGATCATTGCTCCGGCGGATGCGGCGTGGGATGATTTCTTTG
CGGCTCCCGGGGTGGATCTGGGAGAGCGAAACCAGCCGGCCATGCAGGAACGTGAGGCGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A094ZE42

References