Detailed information of TA system TA076723

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 34307..34959
• Replicon: plasmid pAP1342-5
• Accession: NZ_CP021514
• Organism: Acetobacter pasteurianus subsp. Pasteurianus strain SRCM101342

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: S1001342_RS15960
• Protein ID: WP_087652394.1
• Coordinates: 34672..34959 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A1Y0YF37
• Locus tag: S1001342_RS15955
• Protein ID: WP_042789025.1
• Coordinates: 34307..34552 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
S1001342_RS15940	32451..33170	+	720	WP_087652392.1	hypothetical protein	-
S1001342_RS15945	33252..34013	+	762	WP_087652393.1	hypothetical protein	-
S1001342_RS15950	34021..34317	-	297	WP_042789027.1	type II toxin-antitoxin system RelE/ParE family toxin	-
S1001342_RS15955	34307..34552	-	246	WP_042789025.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
S1001342_RS15960	34672..34959	-	288	WP_087652394.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
S1001342_RS15965	34919..35179	-	261	WP_087652405.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	-
S1001342_RS15970	35402..36862	-	1461	WP_087652395.1	phage major capsid protein	-
S1001342_RS15975	37025..37681	-	657	WP_087652396.1	HK97 family phage prohead protease	-
S1001342_RS15980	37699..38979	-	1281	WP_087652397.1	phage portal protein	-
S1001342_RS15985	39646..39825	-	180	WP_087652398.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..43021	43021

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (88-150)

Antitoxin

• Vibrio phage ICP1, Orf50 (8-86)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 14146.97 Da
• Isoelectric Point: 5.5500

>T76723 WP_087652394.1 NZ_CP021514:c34959-34672 [Acetobacter pasteurianus subsp. Pasteurianus]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFF

Nucleotide

• Length: 288 bp

>T76723 NZ_CP021514:c34959-34672 [Acetobacter pasteurianus subsp. Pasteurianus]
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Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 12086.50 Da
• Isoelectric Point: 5.5500

>AT76723 WP_042789025.1 NZ_CP021514:c34552-34307 [Acetobacter pasteurianus subsp. Pasteurianus]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FF

Nucleotide

• Length: 246 bp

>AT76723 NZ_CP021514:c34552-34307 [Acetobacter pasteurianus subsp. Pasteurianus]
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Structures

Antitoxin

• AlphaFold DB: A0A1Y0YF37