76721

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 4447..5117 Replicon plasmid pAP1342-4
Accession NZ_CP021513
Organism Acetobacter pasteurianus subsp. Pasteurianus strain SRCM101342

Toxin (Protein)


Gene name vapC Uniprot ID A0A1A0DIS5
Locus tag S1001342_RS15685 Protein ID WP_064775898.1
Coordinates 4695..5117 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A401X711
Locus tag S1001342_RS15680 Protein ID WP_062144457.1
Coordinates 4447..4698 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
S1001342_RS15660 1..423 + 423 WP_064775896.1 putative toxin-antitoxin system toxin component, PIN family -
S1001342_RS15665 517..774 - 258 WP_064775897.1 conjugal transfer protein TraD -
S1001342_RS15670 839..1198 - 360 WP_196767348.1 conjugal transfer protein TraD -
S1001342_RS15675 1295..4381 + 3087 WP_064775901.1 Ti-type conjugative transfer relaxase TraA -
S1001342_RS15680 4447..4698 + 252 WP_062144457.1 hypothetical protein Antitoxin
S1001342_RS15685 4695..5117 + 423 WP_064775898.1 type II toxin-antitoxin system VapC family toxin Toxin
S1001342_RS15690 5321..5788 + 468 WP_081273878.1 hypothetical protein -
S1001342_RS15695 5874..7613 - 1740 WP_087652355.1 Hint domain-containing protein -
S1001342_RS15700 7826..8422 + 597 WP_064775890.1 recombinase family protein -
S1001342_RS15710 9020..9517 + 498 WP_081273877.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..19899 19899


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 18090.56 Da        Isoelectric Point: 12.9461

>T76721 WP_064775898.1 NZ_CP021513:4695-5117 [Acetobacter pasteurianus subsp. Pasteurianus]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 423 bp

>T76721 NZ_CP021513:4695-5117 [Acetobacter pasteurianus subsp. Pasteurianus]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 10784.64 Da        Isoelectric Point: 12.7191

>AT76721 WP_062144457.1 NZ_CP021513:4447-4698 [Acetobacter pasteurianus subsp. Pasteurianus]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKK

Download         Length: 252 bp

>AT76721 NZ_CP021513:4447-4698 [Acetobacter pasteurianus subsp. Pasteurianus]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1A0DIS5

Antitoxin

Source ID Structure
AlphaFold DB A0A401X711

References