Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1-VagC |
| Location | 155808..156487 | Replicon | plasmid pAP1342-3 |
| Accession | NZ_CP021512 | ||
| Organism | Acetobacter pasteurianus subsp. Pasteurianus strain SRCM101342 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | A0A401X8K4 |
| Locus tag | S1001342_RS15115 | Protein ID | WP_042788834.1 |
| Coordinates | 156077..156487 (+) | Length | 137 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | A0A401X8M0 |
| Locus tag | S1001342_RS15110 | Protein ID | WP_064776521.1 |
| Coordinates | 155808..156080 (+) | Length | 91 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| S1001342_RS15075 | 151241..151525 | - | 285 | WP_087652351.1 | hypothetical protein | - |
| S1001342_RS15080 | 151530..151880 | - | 351 | WP_087652301.1 | hypothetical protein | - |
| S1001342_RS15085 | 152434..153114 | + | 681 | WP_087652302.1 | hypothetical protein | - |
| S1001342_RS15090 | 153173..153472 | + | 300 | WP_157668617.1 | hypothetical protein | - |
| S1001342_RS16390 | 153465..153611 | + | 147 | WP_185369070.1 | hypothetical protein | - |
| S1001342_RS15095 | 154336..154824 | + | 489 | WP_064776524.1 | single-stranded DNA-binding protein | - |
| S1001342_RS15100 | 154887..155324 | + | 438 | WP_087652304.1 | plasmid protein | - |
| S1001342_RS15105 | 155321..155737 | + | 417 | WP_087652305.1 | hypothetical protein | - |
| S1001342_RS15110 | 155808..156080 | + | 273 | WP_064776521.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
| S1001342_RS15115 | 156077..156487 | + | 411 | WP_042788834.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| S1001342_RS15125 | 156919..157128 | + | 210 | WP_080587142.1 | hypothetical protein | - |
| S1001342_RS15130 | 157191..157370 | - | 180 | WP_003630485.1 | hypothetical protein | - |
| S1001342_RS15135 | 157377..157730 | - | 354 | WP_081273974.1 | hypothetical protein | - |
| S1001342_RS15140 | 157790..158593 | - | 804 | WP_042788842.1 | hypothetical protein | - |
| S1001342_RS15145 | 158689..159153 | - | 465 | WP_042788843.1 | hypothetical protein | - |
| S1001342_RS15150 | 159156..160004 | - | 849 | WP_061500709.1 | hypothetical protein | - |
| S1001342_RS15155 | 160122..160838 | - | 717 | WP_197687406.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..256755 | 256755 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 137 a.a. Molecular weight: 17577.87 Da Isoelectric Point: 12.9335
>T76720 WP_042788834.1 NZ_CP021512:156077-156487 [Acetobacter pasteurianus subsp. Pasteurianus]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
Download Length: 411 bp
>T76720 NZ_CP021512:156077-156487 [Acetobacter pasteurianus subsp. Pasteurianus]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAA
Antitoxin
Download Length: 91 a.a. Molecular weight: 11681.86 Da Isoelectric Point: 12.7542
>AT76720 WP_064776521.1 NZ_CP021512:155808-156080 [Acetobacter pasteurianus subsp. Pasteurianus]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKK
Download Length: 273 bp
>AT76720 NZ_CP021512:155808-156080 [Acetobacter pasteurianus subsp. Pasteurianus]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A401X8K4 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A401X8M0 |