76718

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 60073..60683 Replicon plasmid pAP1342-3
Accession NZ_CP021512
Organism Acetobacter pasteurianus subsp. Pasteurianus strain SRCM101342

Toxin (Protein)


Gene name vapC Uniprot ID A0A1A0DB54
Locus tag S1001342_RS14600 Protein ID WP_064776191.1
Coordinates 60270..60683 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A149VHX1
Locus tag S1001342_RS14595 Protein ID WP_035366454.1
Coordinates 60073..60270 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
S1001342_RS14585 55936..59121 + 3186 WP_087652260.1 type I restriction endonuclease subunit R -
S1001342_RS14590 59360..59890 + 531 WP_087652349.1 hypothetical protein -
S1001342_RS14595 60073..60270 + 198 WP_035366454.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
S1001342_RS14600 60270..60683 + 414 WP_064776191.1 PIN domain-containing protein Toxin
S1001342_RS14605 61066..61566 - 501 WP_061507517.1 MucR family transcriptional regulator -
S1001342_RS14610 61643..62395 - 753 WP_087652261.1 DNA/RNA non-specific endonuclease -
S1001342_RS14615 62848..63120 + 273 WP_087652262.1 hypothetical protein -
S1001342_RS14625 63207..63856 + 650 Protein_55 IS5 family transposase -
S1001342_RS14630 63952..64992 + 1041 WP_012813095.1 IS110 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..256755 256755


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-109)

Antitoxin

Antitoxin CbeA

(11-110)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 17706.04 Da        Isoelectric Point: 12.9367

>T76718 WP_064776191.1 NZ_CP021512:60270-60683 [Acetobacter pasteurianus subsp. Pasteurianus]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 414 bp

>T76718 NZ_CP021512:60270-60683 [Acetobacter pasteurianus subsp. Pasteurianus]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 8477.51 Da        Isoelectric Point: 12.6128

>AT76718 WP_035366454.1 NZ_CP021512:60073-60270 [Acetobacter pasteurianus subsp. Pasteurianus]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 198 bp

>AT76718 NZ_CP021512:60073-60270 [Acetobacter pasteurianus subsp. Pasteurianus]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1A0DB54

Antitoxin

Source ID Structure
AlphaFold DB A0A149VHX1

References