Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 1849692..1850221 Replicon chromosome
Accession NZ_CP021467
Organism Komagataeibacter europaeus strain SRCM101446

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag S101446_RS08510 Protein ID WP_208620495.1
Coordinates 1849985..1850221 (+) Length 79 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag S101446_RS08505 Protein ID WP_087608129.1
Coordinates 1849692..1849934 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
S101446_RS08495 1845036..1848278 - 3243 WP_087608127.1 RNA-directed DNA polymerase -
S101446_RS08500 1848275..1849309 - 1035 WP_165829430.1 toprim domain-containing protein -
S101446_RS08505 1849692..1849934 + 243 WP_087608129.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
S101446_RS08510 1849985..1850221 + 237 WP_208620495.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
S101446_RS08515 1850254..1850520 - 267 WP_087608130.1 DUF2274 domain-containing protein -
S101446_RS08520 1850517..1851725 - 1209 WP_087608131.1 TrbI/VirB10 family protein -
S101446_RS08525 1851722..1852723 - 1002 WP_087608132.1 P-type conjugative transfer protein TrbG -
S101446_RS08530 1852720..1853403 - 684 WP_087608860.1 conjugal transfer protein TrbF -
S101446_RS08535 1853409..1854794 - 1386 WP_087608133.1 P-type conjugative transfer protein TrbL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-71)

Antitoxin

Antitoxin ParD

(3-58)


Sequences

Toxin        


Download         Length: 79 a.a.        Molecular weight: 9283.65 Da        Isoelectric Point: 7.0738

>T76701 WP_208620495.1 NZ_CP021467:1849985-1850221 [Komagataeibacter europaeus]
VRDFGPRQAEIYHAGLADAFDLIASHPQLAPERREFDPPIRLHRHRAHHILYLIDDDGVLIVRMLPRLRRWERLIETD

Download         Length: 237 bp

>T76701 NZ_CP021467:1849985-1850221 [Komagataeibacter europaeus]
GTGAGGGATTTTGGGCCACGGCAGGCCGAAATCTACCATGCAGGACTGGCAGACGCGTTCGACCTTATTGCCTCACATCC
GCAGCTTGCGCCGGAACGTCGTGAGTTCGACCCACCGATACGGCTCCACCGTCATCGGGCTCACCATATCCTCTATCTCA
TTGACGACGATGGGGTTCTGATCGTCCGCATGCTGCCCCGACTACGGCGCTGGGAGCGGCTTATAGAAACAGACTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8731.81 Da        Isoelectric Point: 5.7808

>AT76701 WP_087608129.1 NZ_CP021467:1849692-1849934 [Komagataeibacter europaeus]
MATMNVSLPAPMKEWVEAQAKTGRYSNASDYVRDLIRRDQEARAAPDEVQAHITAGVGTRSMKQLLQDARAIAGTTDADL

Download         Length: 243 bp

>AT76701 NZ_CP021467:1849692-1849934 [Komagataeibacter europaeus]
ATGGCAACAATGAACGTATCCCTGCCCGCCCCCATGAAGGAATGGGTAGAGGCTCAGGCCAAGACGGGACGCTATAGCAA
TGCGAGCGACTATGTTCGCGATCTGATCCGGCGAGATCAGGAGGCCCGTGCGGCGCCTGACGAGGTTCAGGCCCACATCA
CGGCCGGTGTGGGGACCAGAAGCATGAAGCAGTTGCTGCAGGATGCTCGCGCGATTGCCGGGACAACGGATGCCGACCTA
TAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References