Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 2037543..2038153 Replicon plasmid pSEPPX05
Accession NZ_CP021449
Organism Ralstonia solanacearum strain SEPPX05

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag RSSE_RS27385 Protein ID WP_087452979.1
Coordinates 2037543..2037851 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag RSSE_RS27390 Protein ID WP_016722339.1
Coordinates 2037848..2038153 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RSSE_RS27365 2033859..2034458 - 600 WP_064478235.1 GNAT family N-acetyltransferase -
RSSE_RS27370 2034591..2035142 + 552 WP_011003399.1 helix-turn-helix transcriptional regulator -
RSSE_RS27375 2035320..2036141 + 822 WP_087452977.1 GntR family transcriptional regulator -
RSSE_RS27380 2036268..2037467 + 1200 WP_087452978.1 MFS transporter -
RSSE_RS27385 2037543..2037851 + 309 WP_087452979.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RSSE_RS27390 2037848..2038153 + 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
RSSE_RS27395 2038366..2039679 + 1314 WP_029240574.1 metabolite/H+ symporter -
RSSE_RS27400 2039829..2040634 + 806 Protein_1671 IS5 family transposase -
RSSE_RS27405 2040699..2041501 + 803 WP_086004752.1 IS5-like element IS1421 family transposase -
RSSE_RS28045 2041680..2041832 - 153 WP_157699215.1 hypothetical protein -
RSSE_RS27415 2041831..2042652 + 822 WP_011004901.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - motA / cheW / cheB / cheY / adeG / acrB / fliI / fliG / fliM / flgG / flgC / cyaB 1..2066085 2066085


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-88)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11922.68 Da        Isoelectric Point: 6.7128

>T76674 WP_087452979.1 NZ_CP021449:2037543-2037851 [Ralstonia solanacearum]
MLTIRTTEIFDDWFCSLRDKAAQRRIQVRIDRLQMGHPGDMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCDGDKS
TQETDIRRAIDLSRRLDVDDME

Download         Length: 309 bp

>T76674 NZ_CP021449:2037543-2037851 [Ralstonia solanacearum]
ATGCTGACGATCCGCACGACCGAAATCTTCGACGACTGGTTTTGCAGCCTCCGCGACAAGGCTGCGCAACGCCGCATCCA
GGTGCGCATCGACCGCCTGCAGATGGGCCACCCAGGCGACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCG
ATCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGACGGCGACAAGTCG
ACGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGATGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT76674 WP_016722339.1 NZ_CP021449:2037848-2038153 [Ralstonia solanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT76674 NZ_CP021449:2037848-2038153 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References