Detailed information of TA system TA076623

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RelB
• Location: 73887..74448
• Replicon: plasmid pSMR4r-1
• Accession: NZ_CP021432
• Organism: Yoonia vestfoldensis strain SMR4r

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LOKVESSMR4R_RS19600
• Protein ID: WP_087213739.1
• Coordinates: 73887..74162 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LOKVESSMR4R_RS19605
• Protein ID: WP_087213742.1
• Coordinates: 74155..74448 (-)
• Length: 98 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LOKVESSMR4R_RS19590	69928..72450	-	2523	WP_087213737.1	strawberry notch family protein	-
LOKVESSMR4R_RS19600	73887..74162	-	276	WP_087213739.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LOKVESSMR4R_RS19605	74155..74448	-	294	WP_087213742.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
LOKVESSMR4R_RS19610	74517..75172	-	656	Protein_63	hypothetical protein	-
LOKVESSMR4R_RS19615	75274..75867	-	594	WP_087213777.1	regulator	-
LOKVESSMR4R_RS19620	75975..77957	-	1983	WP_087213744.1	ParB/RepB/Spo0J family partition protein	-
LOKVESSMR4R_RS19625	78117..78506	-	390	WP_087213746.1	DUF3768 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..111030	111030

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-54)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10272.73 Da
• Isoelectric Point: 4.4287

>T76623 WP_087213739.1 NZ_CP021432:c74162-73887 [Yoonia vestfoldensis]
VPDLEWKATAIADLLAIIDYISDDNPDAAQALKDEIEAKTSRLPERPQMYRVGRVDGTREMVVRPNYIVIYADDPSAIVI
LRVLHAAQQWP

Nucleotide

• Length: 276 bp

>T76623 NZ_CP021432:c74162-73887 [Yoonia vestfoldensis]
GTGCCTGATCTTGAGTGGAAGGCCACGGCCATCGCTGATCTGCTGGCAATTATCGACTACATTTCTGACGACAATCCAGA
TGCGGCCCAAGCTCTCAAGGACGAAATCGAGGCCAAGACATCAAGGTTGCCTGAGCGCCCCCAGATGTACCGTGTGGGAC
GTGTTGACGGCACCCGGGAAATGGTTGTGCGTCCAAATTACATCGTGATCTATGCTGACGACCCAAGTGCCATAGTGATC
TTGCGGGTGCTGCACGCAGCTCAGCAATGGCCATAG

Antitoxin

Protein

• Length: 98 a.a.
• Molecular weight: 10430.84 Da
• Isoelectric Point: 5.0162

>AT76623 WP_087213742.1 NZ_CP021432:c74448-74155 [Yoonia vestfoldensis]
MPAQTSMIHVRVDDQLKAQASDALSGVGLTLSDAVRILLTRVAAEGGLPAGLTADPDAYDAWFRSKVQEALDDPRPTTPQ
AQVMQDAQAMIDKKRRA

Nucleotide

• Length: 294 bp

>AT76623 NZ_CP021432:c74448-74155 [Yoonia vestfoldensis]
ATGCCCGCTCAAACATCCATGATCCATGTCCGTGTTGATGATCAGCTTAAAGCGCAGGCCTCGGATGCGCTCTCGGGCGT
CGGCCTGACACTCTCGGATGCCGTTCGCATCCTCTTGACCCGTGTAGCCGCGGAGGGCGGGTTGCCGGCGGGACTGACAG
CAGATCCAGACGCCTATGACGCATGGTTCCGCTCCAAGGTGCAAGAAGCATTGGACGACCCACGGCCGACAACACCGCAG
GCTCAGGTAATGCAAGACGCTCAGGCGATGATTGACAAGAAGCGCCGTGCCTGA