Detailed information of TA system TA076620

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 3114185..3114710
• Replicon: chromosome
• Accession: NZ_CP021431
• Organism: Yoonia vestfoldensis strain SMR4r

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LOKVESSMR4R_RS15630
• Protein ID: WP_087210409.1
• Coordinates: 3114185..3114475 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LOKVESSMR4R_RS15635
• Protein ID: WP_087210412.1
• Coordinates: 3114465..3114710 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LOKVESSMR4R_RS15605	3109685..3110284	+	600	WP_087210395.1	hypothetical protein	-
LOKVESSMR4R_RS15610	3110284..3110844	+	561	WP_087210398.1	hypothetical protein	-
LOKVESSMR4R_RS15615	3110847..3111257	+	411	WP_157898249.1	hypothetical protein	-
LOKVESSMR4R_RS15620	3111261..3113855	+	2595	WP_087210402.1	host specificity protein J	-
LOKVESSMR4R_RS15625	3113958..3114188	+	231	WP_087210405.1	hypothetical protein	-
LOKVESSMR4R_RS15630	3114185..3114475	-	291	WP_087210409.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LOKVESSMR4R_RS15635	3114465..3114710	-	246	WP_087210412.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
LOKVESSMR4R_RS15640	3114808..3115119	+	312	WP_087210415.1	phage holin family protein	-
LOKVESSMR4R_RS15645	3115217..3116140	+	924	WP_087213397.1	TIGR02594 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-71)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10883.67 Da
• Isoelectric Point: 10.5831

>T76620 WP_087210409.1 NZ_CP021431:c3114475-3114185 [Yoonia vestfoldensis]
MSYELQFLPSALKEWDKLGATLQSQFKKKLKERLAQPHVVADGLHGMPSHYKIKLRSAGYRLVYRVEDTAVTVTVVAVGK
RERNAVYKAAQKRADP

Nucleotide

• Length: 291 bp

>T76620 NZ_CP021431:c3114475-3114185 [Yoonia vestfoldensis]
ATGAGCTATGAGCTGCAATTCCTGCCGTCAGCCCTCAAAGAGTGGGACAAACTTGGCGCAACGCTGCAGTCGCAGTTCAA
AAAGAAGCTAAAAGAGCGACTGGCTCAGCCCCATGTTGTTGCTGACGGCCTGCACGGCATGCCGAGCCACTACAAAATCA
AGCTGCGCAGCGCGGGCTATCGCCTCGTTTACCGCGTTGAAGACACCGCTGTCACGGTAACGGTGGTGGCTGTGGGCAAA
CGCGAGCGGAACGCCGTTTATAAGGCAGCACAGAAACGTGCTGACCCTTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9061.39 Da
• Isoelectric Point: 5.0613

>AT76620 WP_087210412.1 NZ_CP021431:c3114710-3114465 [Yoonia vestfoldensis]
MQRVEANVAVSVSDLKKNPSQVMAMAHGESVAVLNHNRVMAYMVPAARYEAMMEHLDDLELAETIKHRADETPVRVSLDE
L

Nucleotide

• Length: 246 bp

>AT76620 NZ_CP021431:c3114710-3114465 [Yoonia vestfoldensis]
ATGCAACGGGTCGAAGCCAATGTCGCTGTGAGCGTCTCGGACCTCAAAAAAAACCCGTCGCAGGTCATGGCTATGGCGCA
TGGCGAGTCCGTTGCCGTGCTGAACCACAACCGTGTCATGGCCTATATGGTGCCGGCCGCGCGCTATGAGGCAATGATGG
AGCATCTTGACGATTTGGAGCTGGCCGAGACGATCAAGCACCGTGCCGACGAGACACCGGTTCGGGTCAGCTTGGATGAG
CTATGA