Detailed information of TA system TA076619

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2562663..2563188
• Replicon: chromosome
• Accession: NZ_CP021431
• Organism: Yoonia vestfoldensis strain SMR4r

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LOKVESSMR4R_RS12830
• Protein ID: WP_087208972.1
• Coordinates: 2562663..2562953 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LOKVESSMR4R_RS12835
• Protein ID: WP_087208974.1
• Coordinates: 2562943..2563188 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LOKVESSMR4R_RS12805	2558266..2558865	+	600	WP_087208963.1	hypothetical protein	-
LOKVESSMR4R_RS12810	2558865..2559425	+	561	WP_087208965.1	hypothetical protein	-
LOKVESSMR4R_RS12815	2559440..2559838	+	399	WP_087213178.1	hypothetical protein	-
LOKVESSMR4R_RS12820	2559842..2562436	+	2595	WP_087208967.1	host specificity protein J	-
LOKVESSMR4R_RS12825	2562436..2562666	+	231	WP_087208969.1	hypothetical protein	-
LOKVESSMR4R_RS12830	2562663..2562953	-	291	WP_087208972.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LOKVESSMR4R_RS12835	2562943..2563188	-	246	WP_087208974.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
LOKVESSMR4R_RS12840	2563286..2563597	+	312	WP_087208976.1	phage holin family protein	-
LOKVESSMR4R_RS12845	2563698..2564504	+	807	WP_087213183.1	TIGR02594 family protein	-
LOKVESSMR4R_RS12850	2564888..2565928	-	1041	WP_087213186.1	IS110 family transposase	-
LOKVESSMR4R_RS12855	2566212..2566469	+	258	WP_087208978.1	hypothetical protein	-
LOKVESSMR4R_RS12860	2566602..2566955	+	354	WP_087208981.1	hypothetical protein	-
LOKVESSMR4R_RS12865	2566952..2567158	+	207	WP_087208985.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-82)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-71)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10968.82 Da
• Isoelectric Point: 10.8212

>T76619 WP_087208972.1 NZ_CP021431:c2562953-2562663 [Yoonia vestfoldensis]
MSYELQFLPSALKEWDKLGATLQSQFKKKLKERLAQPHVVADRLHGMPSHYKIKLRSAGYRLVYRVEDTTVTVTVVAVGK
RERNAVYKAAQKRAAP

Nucleotide

• Length: 291 bp

>T76619 NZ_CP021431:c2562953-2562663 [Yoonia vestfoldensis]
ATGAGCTATGAGCTGCAATTCCTGCCGTCAGCCCTCAAAGAATGGGACAAACTCGGCGCAACGCTGCAGTCGCAGTTCAA
AAAGAAGCTAAAAGAGCGACTTGCTCAGCCCCATGTTGTTGCTGATCGCCTGCACGGCATGCCGAGCCACTACAAAATCA
AGCTGCGCAGCGCGGGCTATCGCCTCGTTTACCGCGTTGAGGACACCACTGTCACGGTAACAGTGGTGGCTGTGGGCAAA
CGCGAGCGGAACGCCGTTTATAAAGCCGCGCAGAAACGTGCTGCCCCCTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9052.38 Da
• Isoelectric Point: 4.7724

>AT76619 WP_087208974.1 NZ_CP021431:c2563188-2562943 [Yoonia vestfoldensis]
MQRVEANVAVSVSDLKKNPSQVMAMAHGESVAVLNHNRVMAYMVPAARYEAMMEHLDDLELAETIKQRADETPVRVSLDE
L

Nucleotide

• Length: 246 bp

>AT76619 NZ_CP021431:c2563188-2562943 [Yoonia vestfoldensis]
ATGCAGCGGGTCGAAGCCAATGTCGCTGTGAGCGTCTCGGACCTCAAAAAAAACCCGTCGCAGGTCATGGCGATGGCGCA
TGGCGAGTCCGTTGCTGTGCTGAACCATAACCGTGTCATGGCTTATATGGTGCCCGCCGCGCGCTATGAGGCGATGATGG
AGCATCTTGACGACTTGGAGCTGGCCGAGACCATCAAACAACGTGCCGATGAGACACCGGTTCGGGTCAGCTTGGATGAG
CTATGA