Detailed information of TA system TA076617

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-Phd
• Location: 454089..454636
• Replicon: chromosome
• Accession: NZ_CP021430
• Organism: Cellulomonas sp. PSBB021

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CBP52_RS01990
• Protein ID: WP_094179608.1
• Coordinates: 454361..454636 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CBP52_RS01985
• Protein ID: WP_094179607.1
• Coordinates: 454089..454364 (+)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CBP52_RS01960	450951..451268	+	318	WP_094179602.1	hypothetical protein	-
CBP52_RS01965	451265..452092	+	828	WP_094179603.1	hypothetical protein	-
CBP52_RS01970	452095..452493	+	399	WP_094179604.1	YbaB/EbfC family nucleoid-associated protein	-
CBP52_RS01975	452480..453223	+	744	WP_094179605.1	hypothetical protein	-
CBP52_RS01980	453370..453801	-	432	WP_094179606.1	SUKH-3 domain-containing protein	-
CBP52_RS01985	454089..454364	+	276	WP_094179607.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CBP52_RS01990	454361..454636	+	276	WP_094179608.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CBP52_RS01995	454664..455740	-	1077	WP_094179609.1	glycosyltransferase	-
CBP52_RS02000	455920..458286	-	2367	Protein_397	sodium-translocating pyrophosphatase	-
CBP52_RS02005	458621..458851	-	231	WP_094179610.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (11-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-69)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10417.98 Da
• Isoelectric Point: 10.6666

>T76617 WP_094179608.1 NZ_CP021430:454361-454636 [Cellulomonas sp. PSBB021]
VSEAAEPWRVQVAASALRSLERLPPRVVGAVVEFVTRTLPTNPERMSKPLRYELEGLRSARRGDYRVLFTLDDDTRVLLV
VRISHRADAYR

Nucleotide

• Length: 276 bp

>T76617 NZ_CP021430:454361-454636 [Cellulomonas sp. PSBB021]
GTGAGCGAGGCCGCCGAACCGTGGCGGGTCCAGGTCGCGGCGAGCGCGCTGCGCTCGCTCGAGCGTCTGCCCCCGCGCGT
CGTCGGGGCCGTCGTGGAGTTCGTCACCCGGACCCTCCCGACCAACCCCGAGCGCATGTCCAAGCCGCTGCGCTATGAGC
TCGAGGGGCTGCGCTCCGCGCGCCGCGGCGACTACCGCGTCCTGTTCACCCTCGACGACGACACCCGAGTGCTCCTGGTG
GTGCGGATCTCCCACCGGGCCGACGCCTACCGCTGA

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 9898.16 Da
• Isoelectric Point: 4.8134

>AT76617 WP_094179607.1 NZ_CP021430:454089-454364 [Cellulomonas sp. PSBB021]
MRTVALSEAKDKLSALVDEADRTHEIIQITKHGRSAAVLMSADDLDSLHETLFWLSQPGVREDVAAARQAVAEATTISGE
DLRARYGLPPL

Nucleotide

• Length: 276 bp

>AT76617 NZ_CP021430:454089-454364 [Cellulomonas sp. PSBB021]
ATGAGGACTGTCGCTCTGAGCGAGGCGAAGGACAAGCTGTCGGCGCTCGTCGACGAGGCCGACCGCACCCACGAGATCAT
CCAGATCACCAAGCACGGCCGCAGCGCGGCGGTGCTGATGTCGGCGGACGACCTGGACTCCCTGCACGAGACGCTGTTCT
GGCTGTCCCAGCCGGGCGTGCGCGAGGACGTCGCCGCAGCGCGCCAGGCGGTGGCCGAGGCAACGACGATCTCCGGTGAG
GACCTGCGGGCCCGGTACGGCCTCCCGCCGCTGTGA