Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 2166331..2166863 Replicon chromosome
Accession NZ_CP021416
Organism Sulfurospirillum sp. SL2-1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag Sdiek1_RS11020 Protein ID WP_192866743.1
Coordinates 2166331..2166585 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag Sdiek1_RS11025 Protein ID WP_192866744.1
Coordinates 2166582..2166863 (+) Length 94 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Sdiek1_RS11010 2165005..2165631 + 627 WP_161492035.1 LysE family translocator -
Sdiek1_RS11015 2165596..2165952 - 357 WP_087439161.1 hemerythrin family protein -
Sdiek1_RS11020 2166331..2166585 + 255 WP_192866743.1 BrnT family toxin Toxin
Sdiek1_RS11025 2166582..2166863 + 282 WP_192866744.1 CopG family transcriptional regulator Antitoxin
Sdiek1_RS11030 2166872..2167354 - 483 WP_087439163.1 hypothetical protein -
Sdiek1_RS11035 2167452..2167691 - 240 WP_087439164.1 hypothetical protein -
Sdiek1_RS11040 2167704..2167925 - 222 WP_087439165.1 hypothetical protein -
Sdiek1_RS11045 2168223..2169065 + 843 WP_087439166.1 hypothetical protein -
Sdiek1_RS11050 2169185..2169595 + 411 WP_087439167.1 hypothetical protein -
Sdiek1_RS11055 2169826..2170065 + 240 WP_087439168.1 hypothetical protein -
Sdiek1_RS11060 2170224..2170553 + 330 WP_087439169.1 hypothetical protein -
Sdiek1_RS14875 2170550..2170687 + 138 WP_161492036.1 hypothetical protein -
Sdiek1_RS11065 2170687..2171664 + 978 WP_087439170.1 type II and III secretion system protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-80)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 10132.54 Da        Isoelectric Point: 5.6436

>T76608 WP_192866743.1 NZ_CP021416:2166331-2166585 [Sulfurospirillum sp. SL2-1]
MFEYDETKSKANKEKHGIDFEEAQALWQNKQHIVFDSVYVNDEWRHLLVGLIDDLCYVAVFTMREDNIRIISVRRCRKNE
KEIL

Download         Length: 255 bp

>T76608 NZ_CP021416:2166331-2166585 [Sulfurospirillum sp. SL2-1]
ATGTTTGAATACGATGAAACAAAGAGTAAAGCCAATAAAGAAAAACACGGGATTGACTTTGAAGAAGCACAAGCTCTTTG
GCAAAACAAACAACATATAGTTTTTGATAGTGTTTATGTCAATGATGAATGGCGTCATCTTTTAGTTGGTCTTATTGATG
ATCTTTGTTATGTAGCTGTATTCACTATGCGTGAAGATAATATCCGTATTATCAGCGTTAGACGATGTCGAAAAAATGAA
AAGGAAATATTATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10757.57 Da        Isoelectric Point: 9.5957

>AT76608 WP_192866744.1 NZ_CP021416:2166582-2166863 [Sulfurospirillum sp. SL2-1]
MKTISAEEFDKKFDNGEDILPYIDLSSKRTLKEFEKEMLAIKKVNVDLPSWAIASLDQEAKRMGVTRQSIIKMWLIQKLD
DLSLNRKSLKQVG

Download         Length: 282 bp

>AT76608 NZ_CP021416:2166582-2166863 [Sulfurospirillum sp. SL2-1]
ATGAAAACAATATCAGCGGAAGAATTTGATAAAAAATTTGATAATGGTGAAGATATATTACCTTATATTGATCTCTCTTC
AAAAAGAACACTTAAAGAGTTTGAAAAAGAGATGCTAGCTATAAAAAAAGTAAATGTTGATCTTCCATCTTGGGCTATTG
CCTCTTTAGATCAAGAAGCTAAACGTATGGGTGTTACGCGTCAATCTATCATTAAAATGTGGCTTATACAAAAGCTTGAT
GATCTTAGTCTTAACCGTAAGTCTTTAAAGCAAGTGGGATAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References