Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1236585..1237158 Replicon chromosome
Accession NZ_CP021396
Organism Bordetella hinzii strain 4134

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CBR67_RS06230 Protein ID WP_032972650.1
Coordinates 1236871..1237158 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CBR67_RS06225 Protein ID WP_032972652.1
Coordinates 1236585..1236884 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBR67_RS06195 1231674..1231892 + 219 WP_009461157.1 AlpA family transcriptional regulator -
CBR67_RS06200 1231934..1232800 + 867 WP_032972662.1 ParA family protein -
CBR67_RS06205 1232784..1233032 + 249 WP_032972660.1 hypothetical protein -
CBR67_RS06210 1233025..1234683 + 1659 WP_032972657.1 ParB family protein -
CBR67_RS06215 1234701..1235261 + 561 WP_004255086.1 DUF2857 domain-containing protein -
CBR67_RS06220 1235264..1236457 + 1194 WP_032972655.1 hypothetical protein -
CBR67_RS06225 1236585..1236884 + 300 WP_032972652.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CBR67_RS06230 1236871..1237158 + 288 WP_032972650.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CBR67_RS06235 1237187..1237378 + 192 WP_009618207.1 hypothetical protein -
CBR67_RS06240 1237502..1238278 + 777 WP_032972648.1 TIGR03761 family integrating conjugative element protein -
CBR67_RS06245 1238275..1238814 + 540 WP_032972646.1 DUF3158 family protein -
CBR67_RS06250 1238811..1239212 + 402 WP_032972645.1 single-stranded DNA-binding protein -
CBR67_RS06255 1239312..1241018 - 1707 WP_032972643.1 ATP-dependent helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1219009..1247363 28354


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-58)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10868.49 Da        Isoelectric Point: 8.4628

>T76598 WP_032972650.1 NZ_CP021396:1236871-1237158 [Bordetella hinzii]
VRVLEWREAARADLLAIVDYISDDNPDAAQRLKDDIEAKAAKLPERPKLYRPGRVAGTREMIVRANYVVVYMEDTRAVSI
LRVLHAAQQWPPARE

Download         Length: 288 bp

>T76598 NZ_CP021396:1236871-1237158 [Bordetella hinzii]
GTGCGCGTACTTGAGTGGCGGGAAGCTGCCCGCGCCGACCTGCTGGCGATTGTTGACTACATCTCGGACGACAACCCCGA
TGCCGCGCAGCGGTTGAAGGACGACATCGAGGCCAAGGCCGCGAAGCTGCCGGAGCGCCCGAAGCTCTACCGGCCTGGCC
GCGTGGCCGGCACGCGGGAGATGATCGTGCGTGCGAACTACGTGGTGGTCTACATGGAGGACACCCGCGCGGTGTCCATC
CTGCGCGTGTTGCACGCCGCGCAGCAGTGGCCGCCGGCACGGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10788.41 Da        Isoelectric Point: 7.2039

>AT76598 WP_032972652.1 NZ_CP021396:1236585-1236884 [Bordetella hinzii]
MAAQTSMLHIRVDDKLKADAAEKLAGVGLTVSDAVRILLTRVVKEGALPAGLTADPEAYDAWFRAKVQEALADTQPPVPH
QQVMDEAQALIDRKRRART

Download         Length: 300 bp

>AT76598 NZ_CP021396:1236585-1236884 [Bordetella hinzii]
ATGGCCGCACAGACTTCGATGCTGCACATCCGTGTGGACGATAAGCTCAAGGCCGATGCCGCCGAGAAGCTCGCCGGGGT
CGGCCTCACCGTTTCGGACGCCGTGCGCATCCTGCTGACCCGTGTGGTCAAGGAAGGCGCGCTGCCGGCTGGCCTCACGG
CCGACCCGGAGGCCTACGATGCCTGGTTCCGGGCGAAGGTCCAGGAGGCGCTGGCCGACACACAGCCGCCGGTGCCGCAC
CAGCAGGTCATGGACGAGGCGCAGGCCCTGATCGACAGGAAGCGGCGTGCGCGTACTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References