Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 978220..978872 Replicon chromosome
Accession NZ_CP021383
Organism Cellulosimicrobium cellulans strain PSBB019

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CBR64_RS04155 Protein ID WP_087469862.1
Coordinates 978450..978872 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CBR64_RS04150 Protein ID WP_087469861.1
Coordinates 978220..978453 (+) Length 78 a.a.

Genomic Context

CBR64_RS04150CBR64_RS04155CBR64_RS04165CBR64_RS04135CBR64_RS04140CBR64_RS04145CBR64_RS04160CBR64_RS04170
Location: 978220..978453 (234 bp)
Type: Antitoxin
Protein ID: WP_087469861.1
Location: 978450..978872 (423 bp)
Type: Toxin
Protein ID: WP_087469862.1
Location: 980551..981054 (504 bp)
Type: Others
Protein ID: WP_087469863.1
Location: 975227..975781 (555 bp)
Type: Others
Protein ID: WP_047233909.1
Location: 975787..976935 (1149 bp)
Type: Others
Protein ID: WP_087469860.1
Location: 976940..978079 (1140 bp)
Type: Others
Protein ID: WP_087472532.1
Location: 978883..980295 (1413 bp)
Type: Others
Protein ID: WP_087472533.1
Location: 981125..983095 (1971 bp)
Type: Others
Protein ID: WP_167551006.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CBR64_RS04135975227..975781-555WP_047233909.1hypoxanthine phosphoribosyltransferase-
CBR64_RS04140975787..976935-1149WP_087469860.1tRNA lysidine(34) synthetase TilS-
CBR64_RS04145976940..978079-1140WP_087472532.1zinc-dependent metalloprotease-
CBR64_RS04150978220..978453+234WP_087469861.1antitoxinAntitoxin
CBR64_RS04155978450..978872+423WP_087469862.1type II toxin-antitoxin system VapC family toxinToxin
CBR64_RS04160978883..980295-1413WP_087472533.1D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase-
CBR64_RS04165980551..981054+504WP_087469863.1inorganic diphosphatase-
CBR64_RS04170981125..983095-1971WP_167551006.1cell wall-binding repeat-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15199.23 Da        Isoelectric Point: 4.9650

>T76566 WP_087469862.1 NZ_CP021383:978450-978872 [Cellulosimicrobium cellulans]
VSTLYLLDTHVLVALLRGNGSSARPRLREAEGRVAVSTVSEMELEYGIERSSDPHRNRQAVDELLSLVDVLPFDGLAAMH
AGRVRALLAARGTPIGPYDALLAGHARSLGLVMVTNNVREFSRVPGLEVEDWLTEASDEP

Download         Length: 423 bp

>T76566 NZ_CP021383:978450-978872 [Cellulosimicrobium cellulans]
GTGAGCACGCTCTACCTGCTGGACACCCACGTCCTCGTGGCGCTGCTCCGCGGGAACGGCTCGTCGGCGCGCCCGAGGCT
GCGGGAGGCGGAGGGGCGCGTCGCGGTCTCGACGGTGAGCGAGATGGAGCTCGAGTACGGCATCGAGAGGTCTAGCGACC
CGCATCGCAACCGTCAGGCCGTCGACGAGCTGCTGTCTCTCGTGGACGTGCTCCCCTTCGACGGTCTCGCGGCGATGCAC
GCCGGACGCGTCCGCGCCCTCCTCGCCGCCCGCGGCACGCCCATCGGGCCCTACGACGCCCTCCTCGCCGGGCACGCCCG
GTCGCTCGGTCTCGTCATGGTGACGAACAACGTCCGCGAGTTCTCCCGCGTCCCCGGTCTCGAGGTCGAGGACTGGCTCA
CGGAAGCATCAGACGAACCGTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8657.70 Da        Isoelectric Point: 7.2053

>AT76566 WP_087469861.1 NZ_CP021383:978220-978453 [Cellulosimicrobium cellulans]
MVRTTVFRSNRTQAVRLPKAVALPDDVREVEVRAVGRSRVITPAGSGWDEWFDHGLRTAAHFLPDRDQGTAEERDAL

Download         Length: 234 bp

>AT76566 NZ_CP021383:978220-978453 [Cellulosimicrobium cellulans]
ATGGTCCGCACGACGGTGTTCCGCAGCAACCGGACGCAGGCGGTCCGCCTGCCCAAGGCGGTCGCGCTGCCCGACGACGT
CCGGGAGGTGGAGGTCCGGGCCGTCGGCAGGTCCCGAGTGATCACGCCGGCAGGATCCGGGTGGGACGAGTGGTTCGACC
ACGGTCTCCGCACCGCCGCTCACTTCCTCCCCGACCGTGACCAGGGGACCGCCGAGGAGCGCGACGCGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References