76565

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 1794568..1796260 Replicon chromosome
Accession NZ_CP021382
Organism Cellvibrio sp. PSBB006

Toxin (Protein)


Gene name HipA3 Uniprot ID -
Locus tag CBR65_RS07445 Protein ID WP_087466273.1
Coordinates 1794568..1795914 (-) Length 449 a.a.

Antitoxin (Protein)


Gene name HipB3 Uniprot ID -
Locus tag CBR65_RS07450 Protein ID WP_087466274.1
Coordinates 1795901..1796260 (-) Length 120 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBR65_RS07430 1791421..1792500 + 1080 WP_087466270.1 beta-N-acetylglucosaminidase domain-containing protein -
CBR65_RS07435 1792647..1793813 + 1167 WP_087466271.1 glycoside hydrolase family 88 protein -
CBR65_RS07440 1793893..1794549 - 657 WP_087466272.1 alpha/beta hydrolase -
CBR65_RS07445 1794568..1795914 - 1347 WP_087466273.1 type II toxin-antitoxin system HipA family toxin Toxin
CBR65_RS07450 1795901..1796260 - 360 WP_087466274.1 helix-turn-helix transcriptional regulator Antitoxin
CBR65_RS07455 1796601..1797956 + 1356 WP_198300958.1 LOG family protein -
CBR65_RS07460 1798005..1798742 + 738 WP_087466276.1 leucyl/phenylalanyl-tRNA--protein transferase -
CBR65_RS07465 1798949..1799656 + 708 WP_087466277.1 arginyltransferase -
CBR65_RS07470 1799775..1799993 + 219 WP_049722125.1 translation initiation factor IF-1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(17-129)

Antitoxin

Cro/C1-type helix-turn-helix domain

(21-69)


Sequences

Toxin        


Download         Length: 449 a.a.        Molecular weight: 50974.80 Da        Isoelectric Point: 6.3814

>T76565 WP_087466273.1 NZ_CP021382:c1795914-1794568 [Cellvibrio sp. PSBB006]
MSVNKVVEKRHSKVDVADVFIWGTRVGAVAWDDERELGFFEYDPTFLRAPAELAPLMMPRARTIYSFPELDRQSYKGLPG
MLADALPDKFGNLLIDRWLEQQGRDRASFSPVERLCYMGERGMGALEFRPAIKRVQASQPLEIAELAALANRVLSAKSHL
QEQLTDDLSDQRSALGHILAVGTSAGGARAKAVIAWNPETGEVRSGQISAGQGFEHWLLKFDGIAENADKELNDPQGFGR
IEYAYYLMATAADIEMSESRLLEEGGRAHFMTRRFDRRADGDKLHMQSLCAIAHYDFNIAGGYSYEQALQVIKRLNMDSE
KEALEQQYRRMVFNVIARNQDDHTKNIAFLMDRQGNWQLAPAFDVIYSYNPRGEWTSRHQMTVNEKRDDFMLDDLLAVAV
HGNIKTIRAKKIITQVVDAVSEWKTFATRAGVFAEWREEIARHHRLVW

Download         Length: 1347 bp

>T76565 NZ_CP021382:c1795914-1794568 [Cellvibrio sp. PSBB006]
ATGAGCGTGAATAAGGTTGTAGAAAAAAGACATTCCAAAGTCGATGTGGCCGATGTGTTTATTTGGGGTACACGCGTTGG
GGCTGTGGCTTGGGACGATGAGCGGGAGCTGGGCTTTTTTGAGTACGATCCGACATTTTTACGGGCGCCGGCCGAGTTGG
CACCATTGATGATGCCGCGCGCGCGGACTATCTATAGCTTTCCTGAGCTTGATCGCCAATCCTATAAAGGTTTACCGGGC
ATGTTGGCCGATGCTTTGCCGGACAAATTCGGCAATCTGTTGATTGATCGCTGGCTTGAGCAGCAGGGGCGGGATCGGGC
GAGTTTCAGTCCGGTGGAGCGCCTCTGTTATATGGGGGAGCGCGGCATGGGTGCACTGGAATTCCGACCGGCGATCAAGC
GTGTACAAGCGAGTCAGCCGCTGGAAATAGCGGAATTGGCTGCACTGGCCAATCGGGTTTTGTCAGCTAAAAGTCATTTG
CAGGAACAGCTCACGGATGACTTAAGCGATCAGCGTTCGGCATTGGGTCATATCCTCGCTGTGGGAACTTCCGCGGGTGG
TGCGCGAGCCAAGGCCGTAATTGCCTGGAACCCGGAAACGGGAGAAGTCCGTTCCGGCCAGATTTCTGCGGGGCAGGGTT
TCGAACATTGGTTATTGAAGTTTGACGGTATTGCTGAAAATGCAGATAAGGAGTTGAACGATCCCCAAGGGTTTGGGCGC
ATTGAATACGCTTACTATCTAATGGCAACAGCGGCAGATATTGAAATGTCTGAAAGCCGTTTGCTGGAAGAGGGTGGCCG
TGCGCATTTTATGACGCGTCGTTTTGATCGGCGCGCCGATGGGGACAAGCTGCATATGCAATCCCTGTGCGCCATCGCGC
ATTATGATTTCAATATTGCCGGTGGTTATAGTTATGAGCAGGCATTGCAGGTTATCAAACGCCTGAATATGGACAGTGAG
AAAGAGGCGTTGGAACAGCAATATCGGCGCATGGTATTTAATGTGATAGCACGCAACCAGGATGATCACACCAAAAATAT
TGCATTCCTTATGGATCGGCAGGGTAATTGGCAATTAGCGCCCGCCTTTGATGTGATTTACAGTTACAATCCACGCGGCG
AATGGACATCACGTCATCAAATGACAGTGAATGAAAAGCGCGATGACTTTATGCTGGATGATTTATTGGCGGTTGCGGTC
CACGGCAATATAAAAACGATTCGGGCCAAAAAAATCATCACGCAGGTTGTTGATGCGGTCAGTGAGTGGAAGACCTTCGC
AACACGCGCCGGTGTTTTTGCTGAATGGCGCGAAGAAATTGCACGGCACCACCGTCTGGTGTGGTAA

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13177.17 Da        Isoelectric Point: 9.2956

>AT76565 WP_087466274.1 NZ_CP021382:c1796260-1795901 [Cellvibrio sp. PSBB006]
MALAFHQLSDQHIHDELCSRLKAARLEINITQAELAERAGISLITVKRAESAKGNITLMTLIALLRALGRLDQLDNFLPL
PALSPLQLKAVGGQRRQRASASREVNEPASGWKWGDERE

Download         Length: 360 bp

>AT76565 NZ_CP021382:c1796260-1795901 [Cellvibrio sp. PSBB006]
ATGGCACTGGCGTTCCATCAATTAAGTGATCAGCACATTCATGATGAATTGTGTAGCCGCCTTAAGGCGGCACGCCTTGA
GATCAATATTACTCAGGCGGAGTTAGCGGAGCGGGCCGGGATCAGTCTGATTACCGTAAAGCGTGCGGAATCTGCCAAGG
GCAATATTACCCTGATGACGTTGATTGCCTTATTGCGCGCGTTGGGGCGACTCGACCAATTGGATAACTTCTTGCCTTTA
CCTGCCTTGAGCCCCTTGCAATTAAAAGCTGTTGGCGGGCAGCGGCGCCAGCGAGCCTCTGCGAGTCGTGAGGTTAATGA
GCCGGCTTCTGGCTGGAAGTGGGGGGATGAGCGTGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References