Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3415638..3416197 Replicon chromosome
Accession NZ_CP021377
Organism Oceanisphaera profunda strain SM1222

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CBP31_RS15110 Protein ID WP_087038476.1
Coordinates 3415638..3415913 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CBP31_RS15115 Protein ID WP_087038477.1
Coordinates 3415910..3416197 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBP31_RS15090 3411031..3411777 + 747 WP_087038472.1 HNH endonuclease -
CBP31_RS15095 3412309..3413061 + 753 WP_161492540.1 cold shock domain-containing protein -
CBP31_RS15100 3413262..3413669 + 408 WP_087038474.1 OsmC family protein -
CBP31_RS15105 3413822..3415534 + 1713 WP_087038475.1 DUF262 domain-containing HNH endonuclease family protein -
CBP31_RS15110 3415638..3415913 - 276 WP_087038476.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CBP31_RS15115 3415910..3416197 - 288 WP_087038477.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CBP31_RS15120 3416445..3416978 - 534 WP_087038478.1 CIA30 family protein -
CBP31_RS15125 3417404..3418012 + 609 WP_087038479.1 hypothetical protein -
CBP31_RS15130 3417989..3418740 - 752 Protein_2898 IS5 family transposase -
CBP31_RS15135 3418890..3419849 - 960 WP_087038480.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3407205..3416197 8992


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-44)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10704.40 Da        Isoelectric Point: 4.5098

>T76557 WP_087038476.1 NZ_CP021377:c3415913-3415638 [Oceanisphaera profunda]
VILWEEESLNDREKIFEFLYDFNPAAADKTDQIIEEKIENLLQQPLMSVQRDDIKGRLLIIPEISMIVSYSVDGSVIRIM
RILHQKQKFPT

Download         Length: 276 bp

>T76557 NZ_CP021377:c3415913-3415638 [Oceanisphaera profunda]
GTGATCTTATGGGAAGAAGAATCTCTGAACGACCGAGAAAAAATTTTTGAATTTCTTTATGACTTTAATCCTGCGGCTGC
AGATAAAACAGATCAGATCATTGAAGAAAAGATAGAAAATTTACTTCAACAGCCATTAATGAGCGTTCAGCGAGATGATA
TAAAAGGTCGATTACTTATAATCCCTGAGATATCAATGATAGTTTCCTATTCAGTTGATGGCTCAGTAATTCGTATCATG
AGAATACTACACCAGAAACAAAAATTTCCGACGTAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10924.19 Da        Isoelectric Point: 7.1691

>AT76557 WP_087038477.1 NZ_CP021377:c3416197-3415910 [Oceanisphaera profunda]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLADQQRKASSHDAWLSEQVNLAFEKLDAGKSTFIEHDQAKSI
MAERKAKIRSRSVNQ

Download         Length: 288 bp

>AT76557 NZ_CP021377:c3416197-3415910 [Oceanisphaera profunda]
ATGGATACTAGAATTCAGTTTCGAGTCGATGAAGAAACCAAACGCTTGGCCCAACAAATGGCTGAGAGCCAAGGCCGTAC
CCTTAGTGATGCTTGTAGAGAACTTACAGAGCAATTAGCTGATCAACAACGTAAAGCCTCGTCTCATGATGCTTGGCTAA
GTGAGCAGGTAAATTTAGCTTTCGAAAAGTTAGATGCCGGAAAGTCTACTTTTATTGAACATGACCAAGCCAAATCTATA
ATGGCAGAACGCAAAGCTAAGATCCGCAGCCGGAGTGTTAATCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References