Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1038023..1038582 Replicon chromosome
Accession NZ_CP021376
Organism Oceanisphaera avium strain AMac2203

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CBP12_RS04720 Protein ID WP_086963410.1
Coordinates 1038307..1038582 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CBP12_RS04715 Protein ID WP_086963409.1
Coordinates 1038023..1038310 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBP12_RS04690 1034541..1034780 - 240 WP_086963405.1 sulfurtransferase-like selenium metabolism protein YedF -
CBP12_RS04695 1034770..1035969 - 1200 WP_086965377.1 selenium metabolism membrane protein YedE/FdhT -
CBP12_RS04700 1036181..1037215 + 1035 WP_086963406.1 sensor domain-containing diguanylate cyclase -
CBP12_RS04705 1037237..1037494 - 258 WP_086963407.1 hypothetical protein -
CBP12_RS04710 1037518..1037856 - 339 WP_086963408.1 thioredoxin family protein -
CBP12_RS04715 1038023..1038310 + 288 WP_086963409.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CBP12_RS04720 1038307..1038582 + 276 WP_086963410.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CBP12_RS04725 1038714..1039253 - 540 WP_086963411.1 hypothetical protein -
CBP12_RS04730 1039545..1040843 - 1299 WP_086963412.1 DNA (cytosine-5-)-methyltransferase -
CBP12_RS04735 1040910..1041626 - 717 WP_086963413.1 restriction endonuclease -
CBP12_RS04740 1041753..1042250 - 498 WP_086963414.1 hypothetical protein -
CBP12_RS04745 1042255..1042674 - 420 WP_086963415.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-69)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10606.30 Da        Isoelectric Point: 4.6286

>T76553 WP_086963410.1 NZ_CP021376:1038307-1038582 [Oceanisphaera avium]
VILWEEESLNDREKIFEFLYDFNPTAADKTDQVIEDKVENLLQQSLMGVQRDGIKGRLLIIPEISMIVSYLVDGSVIRIM
RVLHQKQKFPT

Download         Length: 276 bp

>T76553 NZ_CP021376:1038307-1038582 [Oceanisphaera avium]
GTGATTCTATGGGAAGAAGAATCTCTGAACGACCGAGAAAAAATTTTTGAATTTCTTTATGACTTTAATCCTACGGCTGC
AGATAAAACAGATCAGGTAATTGAAGATAAAGTAGAAAATTTACTTCAACAGTCATTAATGGGCGTGCAACGAGATGGGA
TAAAAGGTCGATTACTCATAATCCCAGAGATATCAATGATAGTTTCCTATTTAGTTGATGGCTCTGTCATTCGTATCATG
AGAGTACTACATCAGAAACAAAAATTTCCGACGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10947.31 Da        Isoelectric Point: 7.1688

>AT76553 WP_086963409.1 NZ_CP021376:1038023-1038310 [Oceanisphaera avium]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRDLTEQLADQQRKALSHDVWLSEQINLAFEKLDAGKSTFIEHDQAKSI
MAERKAKIRSRSVNP

Download         Length: 288 bp

>AT76553 NZ_CP021376:1038023-1038310 [Oceanisphaera avium]
ATGGATACTAGAATTCAGTTTCGAGTCGATGAAGAAACCAAGCGCCTAGCCCAACAAATGGCTGAAAGCCAAGGCCGTAC
CCTTAGTGATGCTTGCAGAGACCTTACGGAACAATTGGCAGATCAACAACGTAAAGCCTTGTCTCATGATGTTTGGCTAA
GTGAGCAAATAAATTTAGCTTTTGAAAAATTAGATGCCGGCAAATCTACTTTTATTGAACATGACCAAGCCAAATCCATA
ATGGCAGAACGTAAAGCTAAGATCCGCAGCCGGAGTGTTAACCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References