Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parE_1-relB/RelE-RelB
Location 140528..141104 Replicon plasmid pRACO34Ab
Accession NZ_CP021374
Organism Rhizobium sp. ACO-34A

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag ACO34A_RS27730 Protein ID WP_099061209.1
Coordinates 140528..140818 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ACO34A_RS27735 Protein ID WP_099061358.1
Coordinates 140805..141104 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACO34A_RS27710 136036..136965 + 930 WP_099061356.1 sugar ABC transporter substrate-binding protein -
ACO34A_RS27715 137046..138584 + 1539 WP_099061207.1 sugar ABC transporter ATP-binding protein -
ACO34A_RS27720 138616..139647 + 1032 WP_099061357.1 ABC transporter permease -
ACO34A_RS27725 139709..140521 + 813 WP_099061208.1 TIM barrel protein -
ACO34A_RS27730 140528..140818 - 291 WP_099061209.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ACO34A_RS27735 140805..141104 - 300 WP_099061358.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
ACO34A_RS27740 141197..142318 - 1122 WP_099061210.1 Gfo/Idh/MocA family oxidoreductase -
ACO34A_RS27745 142367..143176 - 810 WP_099061211.1 5-deoxy-glucuronate isomerase -
ACO34A_RS27750 143250..144158 - 909 WP_099061212.1 myo-inosose-2 dehydratase -
ACO34A_RS27755 144161..145981 - 1821 WP_099061213.1 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - adeG 1..305590 305590


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-58)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11061.58 Da        Isoelectric Point: 6.8697

>T76552 WP_099061209.1 NZ_CP021374:c140818-140528 [Rhizobium sp. ACO-34A]
VLKIEWRQTAREDLLAIIGFITDHNPGAAQRLKDEILSKVLRLTEIHNCIGRDGSPEREKWSFTPTNYIVIYTENDTTIS
ILRVLHGAQQWPPHNT

Download         Length: 291 bp

>T76552 NZ_CP021374:c140818-140528 [Rhizobium sp. ACO-34A]
GTGCTCAAGATTGAGTGGCGTCAGACGGCCCGCGAGGACCTTCTTGCCATCATCGGCTTCATTACGGATCACAATCCCGG
CGCCGCTCAACGGCTCAAGGACGAGATCCTTTCCAAGGTGTTGAGACTGACGGAAATCCACAACTGCATCGGACGGGACG
GGTCTCCGGAACGCGAGAAATGGTCGTTCACGCCAACTAACTACATCGTTATCTACACCGAAAACGATACAACCATCTCA
ATTCTACGCGTGTTGCACGGCGCCCAGCAGTGGCCGCCGCACAATACGTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11089.66 Da        Isoelectric Point: 5.6604

>AT76552 WP_099061358.1 NZ_CP021374:c141104-140805 [Rhizobium sp. ACO-34A]
IMSKTSMLHIRIDEKLKSEASETLATVGLTVSDAVRILLTRITREGGLPAGLTVDPEAHDAWFREKVREALTDDRPPVSH
DVVMDEVQALIDRKRRAQD

Download         Length: 300 bp

>AT76552 NZ_CP021374:c141104-140805 [Rhizobium sp. ACO-34A]
ATTATGTCCAAGACCTCGATGCTTCATATCCGTATCGATGAAAAGCTGAAAAGCGAAGCCTCCGAGACCCTTGCCACGGT
CGGCCTGACGGTCTCCGACGCCGTGAGAATTCTTCTGACTCGCATTACACGTGAAGGCGGGCTTCCAGCCGGCCTCACTG
TCGATCCCGAGGCCCACGATGCCTGGTTTCGTGAAAAGGTACGCGAAGCCTTGACTGACGACCGCCCGCCGGTCTCACAC
GATGTCGTCATGGATGAAGTTCAGGCACTGATCGACAGGAAGCGCCGTGCTCAAGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References