Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 1179462..1180093 Replicon chromosome
Accession NZ_CP021371
Organism Rhizobium sp. ACO-34A

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ACO34A_RS05695 Protein ID WP_099056872.1
Coordinates 1179695..1180093 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ACO34A_RS05690 Protein ID WP_099059896.1
Coordinates 1179462..1179698 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACO34A_RS05660 1174520..1175536 - 1017 WP_099059894.1 polyprenyl synthetase family protein -
ACO34A_RS05665 1175644..1175874 + 231 WP_099056868.1 DUF2007 domain-containing protein -
ACO34A_RS05670 1175979..1176668 + 690 WP_099059895.1 methyltransferase -
ACO34A_RS05675 1176689..1178035 - 1347 WP_099056869.1 Nramp family divalent metal transporter -
ACO34A_RS05680 1178324..1179190 + 867 WP_099056870.1 S49 family peptidase -
ACO34A_RS05685 1179206..1179397 + 192 WP_099056871.1 hypothetical protein -
ACO34A_RS05690 1179462..1179698 + 237 WP_099059896.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
ACO34A_RS05695 1179695..1180093 + 399 WP_099056872.1 PIN domain-containing protein Toxin
ACO34A_RS05700 1180194..1181147 + 954 WP_099056873.1 glycine--tRNA ligase subunit alpha -
ACO34A_RS05705 1181386..1181937 + 552 WP_099056874.1 LemA family protein -
ACO34A_RS05710 1181956..1183890 + 1935 WP_099056875.1 DUF2207 domain-containing protein -
ACO34A_RS05715 1183987..1184373 + 387 WP_099056876.1 DUF559 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-114)

Antitoxin

SpoVT-AbrB domain

(5-36)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14441.75 Da        Isoelectric Point: 4.3933

>T76550 WP_099056872.1 NZ_CP021371:1179695-1180093 [Rhizobium sp. ACO-34A]
MKPPLLDTNILIYAFSDDLKAGRAQECPAQPFVLSTQALNEFANVALRKLGMTAPEVRIAIADICLLAEDIFPLDRRTHE
MALDIAERYHLSFYDSLMLSAACLAGCPSCLSEDMQHGLLIEGGTTVANPFI

Download         Length: 399 bp

>T76550 NZ_CP021371:1179695-1180093 [Rhizobium sp. ACO-34A]
ATGAAGCCCCCTCTCCTTGACACCAATATCCTGATCTATGCTTTCAGCGATGATCTGAAGGCTGGACGTGCACAGGAGTG
TCCTGCGCAACCCTTCGTGCTTTCGACGCAGGCGCTGAATGAATTCGCCAACGTCGCACTTCGCAAACTAGGCATGACGG
CCCCTGAAGTGCGCATTGCCATTGCGGACATCTGCCTATTGGCCGAGGACATATTTCCGCTGGATCGCCGCACCCATGAA
ATGGCGCTCGACATTGCCGAGCGATACCACCTGTCCTTTTACGACAGCCTCATGTTGTCTGCTGCTTGTCTGGCTGGCTG
TCCCTCTTGCCTTTCGGAAGACATGCAGCACGGCCTGCTGATCGAGGGCGGAACGACGGTCGCTAATCCGTTTATCTAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8729.73 Da        Isoelectric Point: 5.1367

>AT76550 WP_099059896.1 NZ_CP021371:1179462-1179698 [Rhizobium sp. ACO-34A]
MQVSRWGNSLAIRIPAAVAEALELKEGDEVNVRVSGSRTFEIGREDSREQALTRIRNARISLPAGWTFDRDEANERCG

Download         Length: 237 bp

>AT76550 NZ_CP021371:1179462-1179698 [Rhizobium sp. ACO-34A]
ATGCAGGTCTCCCGATGGGGCAATAGTCTTGCCATTCGCATTCCTGCCGCCGTTGCCGAAGCGCTTGAACTGAAGGAAGG
CGACGAGGTCAATGTGCGGGTGAGTGGCTCCCGCACTTTCGAGATCGGACGGGAGGATAGCCGGGAACAGGCTCTGACGC
GTATTCGCAACGCGAGGATCAGTCTGCCGGCGGGCTGGACGTTTGATCGCGACGAAGCGAACGAACGCTGCGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References