Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2408732..2409522 Replicon chromosome
Accession NZ_CP021366
Organism Acidovorax carolinensis strain P4

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CBP36_RS11215 Protein ID WP_086927476.1
Coordinates 2408732..2409232 (-) Length 167 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag CBP36_RS11220 Protein ID WP_086927477.1
Coordinates 2409229..2409522 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBP36_RS11195 2404485..2405423 - 939 WP_086927473.1 glycosyltransferase family 2 protein -
CBP36_RS11200 2405420..2406259 - 840 WP_086927474.1 methyltransferase domain-containing protein -
CBP36_RS11205 2406298..2408145 - 1848 WP_086927475.1 hypothetical protein -
CBP36_RS22170 2408574..2408735 - 162 WP_157896735.1 hypothetical protein -
CBP36_RS11215 2408732..2409232 - 501 WP_086927476.1 GNAT family N-acetyltransferase Toxin
CBP36_RS11220 2409229..2409522 - 294 WP_086927477.1 DUF1778 domain-containing protein Antitoxin
CBP36_RS11225 2410208..2411545 - 1338 WP_086910894.1 IS1182 family transposase -
CBP36_RS11230 2411917..2413148 + 1232 WP_094122614.1 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2399937..2409900 9963


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-96)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 18300.18 Da        Isoelectric Point: 9.5707

>T76547 WP_086927476.1 NZ_CP021366:c2409232-2408732 [Acidovorax carolinensis]
VTLRAPEPLAAQHRLEGFDCGKPALNDWLLRHARQAQGSGSAKTFVVAEDDGHVAGYFSLTVGKVDTLEAPERIRKGMGQ
YPLPVVILARLAVSIHDQGRGIGFGLLQDAIRRTMLIAEQAGIRAMLTHPIDDDAAQFYTRFGFIASPLREQQLLLLLKD
AKKFIR

Download         Length: 501 bp

>T76547 NZ_CP021366:c2409232-2408732 [Acidovorax carolinensis]
GTGACGTTGCGCGCACCGGAGCCACTGGCTGCCCAGCATCGGCTGGAAGGTTTTGATTGCGGTAAACCCGCGCTCAACGA
CTGGCTGTTACGCCACGCCCGCCAGGCGCAGGGCAGTGGATCGGCCAAGACCTTCGTTGTTGCCGAGGACGATGGCCACG
TAGCGGGCTACTTCAGCCTGACCGTGGGTAAAGTCGACACGCTGGAGGCACCGGAGCGCATCCGCAAGGGGATGGGGCAG
TACCCTTTGCCAGTGGTGATTCTGGCGAGGCTGGCAGTATCAATTCACGATCAGGGGCGAGGAATCGGCTTTGGCCTGCT
GCAGGATGCGATTCGTCGCACGATGCTGATTGCCGAGCAGGCTGGCATCCGGGCGATGTTGACCCATCCCATCGATGATG
ACGCAGCGCAGTTCTACACCCGTTTCGGGTTCATCGCGTCACCGCTGCGTGAGCAGCAACTTCTGCTGTTGCTGAAGGAT
GCGAAGAAGTTCATCCGATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10703.19 Da        Isoelectric Point: 5.8188

>AT76547 WP_086927477.1 NZ_CP021366:c2409522-2409229 [Acidovorax carolinensis]
MTAVASSPSARSARLGLRATPEQEVVLRRAAEVAHKSLTDFILDSACLAAEQTLLDQRLFMVSGSQYQALMDLLDRPEQA
NDGLRDLFARKAPWDTK

Download         Length: 294 bp

>AT76547 NZ_CP021366:c2409522-2409229 [Acidovorax carolinensis]
ATGACTGCTGTTGCATCGTCGCCTTCCGCACGGTCCGCCCGCCTCGGGCTGCGCGCCACCCCCGAACAGGAGGTGGTGTT
GCGTCGGGCTGCTGAGGTTGCCCACAAGTCGCTGACCGACTTCATTCTCGACAGCGCCTGCCTGGCTGCCGAGCAAACCC
TACTGGATCAGCGCCTGTTTATGGTGTCGGGCAGTCAGTACCAGGCTCTGATGGATCTGCTCGATCGCCCCGAACAGGCC
AACGACGGTTTGCGTGATCTGTTTGCCCGAAAGGCGCCCTGGGACACGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References