Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3579351..3580849 Replicon chromosome
Accession NZ_CP021359
Organism Acidovorax carolinensis strain NA2

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag CBP33_RS16800 Protein ID WP_086913534.1
Coordinates 3579351..3580253 (-) Length 301 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag CBP33_RS16805 Protein ID WP_086913535.1
Coordinates 3580250..3580849 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBP33_RS16775 3575410..3575889 + 480 WP_086913531.1 MaoC family dehydratase N-terminal domain-containing protein -
CBP33_RS16780 3575921..3576907 + 987 WP_086913532.1 tripartite tricarboxylate transporter substrate binding protein -
CBP33_RS16785 3577127..3577561 + 435 WP_086913533.1 hypothetical protein -
CBP33_RS16790 3577598..3578833 - 1236 Protein_3311 IS3 family transposase -
CBP33_RS16795 3578922..3579203 + 282 WP_086914224.1 hypothetical protein -
CBP33_RS16800 3579351..3580253 - 903 WP_086913534.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
CBP33_RS16805 3580250..3580849 - 600 WP_086913535.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
CBP33_RS16810 3581334..3582011 - 678 WP_086913536.1 3-isopropylmalate dehydratase small subunit -
CBP33_RS16815 3582008..3583441 - 1434 WP_086913537.1 3-isopropylmalate dehydratase large subunit -
CBP33_RS16820 3583438..3584343 - 906 WP_086913538.1 alpha/beta hydrolase -
CBP33_RS16825 3584379..3585365 - 987 WP_086913539.1 tripartite tricarboxylate transporter substrate binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(35-257)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(5-52)


Sequences

Toxin        


Download         Length: 301 a.a.        Molecular weight: 33000.81 Da        Isoelectric Point: 5.8971

>T76542 WP_086913534.1 NZ_CP021359:c3580253-3579351 [Acidovorax carolinensis]
MTGNLSASILARLLTLAKQRGDDYNLLLNRFGMERLLARVSLSPHADRFLLKGALLFALWYDTPHRPTRDADLLGFGPDD
EANLISTFREVAAMELGDGIAFDPDSVKADAIREDNTYGGTRITLVARIGSARCALQIDVGFGDAVTPGPQIVTYPTLLG
DFQVPTLRVYPVYTVIAEKYQAMVMLGQANSRMKDFFDLAVIARRTELDGATLAAAIAATFARRQTALPTERPLALTKKF
SEDAAKLRQWQAFLNKNRIEAASLGDTVDLLDDLLWPPTQVAAAKSEATATWRPDSLRWV

Download         Length: 903 bp

>T76542 NZ_CP021359:c3580253-3579351 [Acidovorax carolinensis]
ATGACTGGCAACCTATCCGCGTCGATCCTGGCCCGACTGCTGACCCTCGCCAAGCAACGCGGCGACGACTACAACCTGCT
GCTCAACCGCTTCGGCATGGAACGTCTGCTGGCCCGCGTCAGCCTGTCTCCGCATGCCGATCGCTTCCTGCTCAAGGGCG
CCCTGCTCTTTGCTCTTTGGTATGACACCCCGCACCGGCCGACCAGAGACGCCGACTTGCTCGGCTTCGGCCCCGACGAT
GAGGCGAACCTTATCTCCACTTTCCGCGAAGTCGCCGCCATGGAACTGGGCGACGGCATCGCGTTTGACCCCGACTCCGT
GAAGGCCGATGCCATTCGCGAGGACAACACCTACGGCGGCACCCGCATCACACTGGTAGCGCGTATTGGCTCCGCACGCT
GCGCACTGCAGATCGACGTGGGCTTCGGTGATGCCGTGACGCCGGGGCCGCAGATAGTGACCTATCCTACTTTGCTGGGT
GACTTCCAGGTCCCGACGCTGCGGGTCTATCCGGTCTACACCGTGATCGCCGAGAAGTACCAGGCCATGGTGATGCTGGG
GCAGGCGAACAGCCGCATGAAGGATTTTTTCGATCTCGCGGTGATTGCCCGGCGCACGGAACTGGATGGCGCCACGCTGG
CCGCAGCTATTGCCGCCACCTTTGCACGGCGCCAGACCGCGCTGCCCACTGAGCGCCCCTTGGCCTTGACAAAGAAGTTC
AGCGAAGACGCTGCCAAGCTGCGCCAGTGGCAAGCCTTCCTGAACAAGAACCGCATTGAAGCTGCCAGCCTGGGTGACAC
CGTTGACCTGCTGGACGACCTGCTGTGGCCTCCTACCCAAGTGGCAGCTGCCAAGAGTGAGGCGACGGCTACTTGGCGAC
CCGATTCTTTACGCTGGGTGTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22555.08 Da        Isoelectric Point: 9.7363

>AT76542 WP_086913535.1 NZ_CP021359:c3580849-3580250 [Acidovorax carolinensis]
MNQSDQILELARHRRVLRAADVRAHGWSPQLLIRLHQAGKLQRFTRGLYGLPDTEITEHQTLIEVCQRVPKAVLCLLSAL
QFHEIGTQLPHEVWIALPEATQTPALSYPTLRITRLRGAAYSDGIQTVTDHGASIRVYSAAKTVTDCFKFRNKIGLDVAL
EALKDAWHSRKVTMVELSHFAKINRVERVMQPYLEAVTQ

Download         Length: 600 bp

>AT76542 NZ_CP021359:c3580849-3580250 [Acidovorax carolinensis]
ATGAACCAATCGGATCAAATCCTTGAGCTGGCCCGTCACCGGCGTGTGCTGCGGGCGGCCGATGTGCGGGCGCACGGCTG
GTCGCCGCAGCTTCTGATCCGACTGCATCAGGCCGGTAAGCTGCAGCGCTTCACCCGCGGCCTGTACGGGCTGCCCGATA
CCGAAATCACCGAACACCAGACGCTGATCGAGGTCTGCCAGCGCGTGCCAAAGGCCGTGCTGTGTCTGCTGAGCGCACTG
CAATTTCACGAGATCGGCACGCAACTGCCGCACGAAGTGTGGATCGCGCTGCCCGAGGCGACACAGACCCCGGCGCTGAG
CTACCCCACGCTGCGCATCACACGTCTGCGCGGTGCCGCGTACAGCGACGGCATCCAGACCGTGACCGACCACGGTGCAT
CCATCCGCGTGTACAGCGCCGCCAAGACGGTGACCGACTGCTTCAAGTTCCGCAACAAGATCGGCCTGGACGTGGCGCTG
GAGGCTCTGAAAGATGCCTGGCACAGCCGCAAGGTCACCATGGTCGAGCTGAGCCACTTCGCCAAAATCAACCGGGTTGA
ACGTGTCATGCAGCCCTACCTAGAGGCGGTGACGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References