Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1702397..1703041 Replicon chromosome
Accession NZ_CP021359
Organism Acidovorax carolinensis strain NA2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CBP33_RS08095 Protein ID WP_086912098.1
Coordinates 1702397..1702810 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag CBP33_RS08100 Protein ID WP_086912099.1
Coordinates 1702811..1703041 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBP33_RS08070 1698176..1698688 + 513 WP_086912095.1 hypothetical protein -
CBP33_RS08075 1699242..1699556 + 315 WP_162290792.1 DUF1640 domain-containing protein -
CBP33_RS19315 1700220..1700618 - 399 WP_086912097.1 hypothetical protein -
CBP33_RS08090 1700790..1702021 + 1232 WP_157896558.1 IS3 family transposase -
CBP33_RS08095 1702397..1702810 - 414 WP_086912098.1 type II toxin-antitoxin system VapC family toxin Toxin
CBP33_RS08100 1702811..1703041 - 231 WP_086912099.1 antitoxin Antitoxin
CBP33_RS19095 1703428..1703721 + 294 WP_157896559.1 hypothetical protein -
CBP33_RS08105 1703645..1704547 - 903 WP_086912100.1 hypothetical protein -
CBP33_RS08110 1704544..1704864 - 321 WP_086912101.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1692731..1773528 80797


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-127)

Antitoxin

SpoVT-AbrB domain

(7-43)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15092.24 Da        Isoelectric Point: 7.4220

>T76539 WP_086912098.1 NZ_CP021359:c1702810-1702397 [Acidovorax carolinensis]
MAVRYLLDTNICIYIAKHNPPAVRARFEQLSADALAMSVITLGELQHGAEKSQARAKALVALEQLQSAIQVMPLTHAAGQ
HYGQIRSALERAGQPIGNNDLWIAAHARAEGWVLVTNNEREFRRVDGLAVENWVTPT

Download         Length: 414 bp

>T76539 NZ_CP021359:c1702810-1702397 [Acidovorax carolinensis]
ATGGCCGTCCGCTACCTGCTTGACACCAACATCTGCATCTACATCGCCAAGCACAACCCGCCCGCCGTGCGAGCGCGGTT
TGAGCAGCTCAGCGCAGACGCACTGGCCATGTCGGTCATTACCCTGGGCGAGCTGCAGCACGGCGCAGAAAAAAGCCAGG
CCCGGGCCAAAGCCCTAGTAGCGCTGGAGCAGCTGCAAAGCGCCATCCAGGTAATGCCATTGACCCACGCCGCAGGCCAG
CACTACGGCCAGATCCGAAGCGCCTTGGAGCGAGCGGGGCAGCCCATCGGCAATAACGATCTCTGGATAGCCGCCCATGC
TCGTGCCGAAGGCTGGGTGCTGGTGACCAACAACGAGCGCGAGTTCCGCCGTGTGGATGGCCTGGCGGTAGAAAACTGGG
TCACACCTACGTAG

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8546.51 Da        Isoelectric Point: 4.6855

>AT76539 WP_086912099.1 NZ_CP021359:c1703041-1702811 [Acidovorax carolinensis]
MTYARVFQSGNSQAVRLPKEFRFNAEQVEIFRQGNDIVLREHPTSAAAIFDALASLPADFMQAGRDDTAPQEREAF

Download         Length: 231 bp

>AT76539 NZ_CP021359:c1703041-1702811 [Acidovorax carolinensis]
ATGACCTACGCTCGCGTCTTCCAGTCCGGCAACAGCCAGGCCGTGCGCTTGCCCAAAGAGTTCCGCTTCAACGCAGAGCA
GGTGGAGATCTTTCGGCAGGGCAACGACATCGTCCTGCGCGAACACCCAACTAGTGCCGCTGCCATCTTCGATGCCCTGG
CCAGCCTGCCTGCCGACTTCATGCAAGCAGGCCGCGATGACACGGCTCCTCAAGAGCGGGAGGCCTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References