Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2254915..2255149 | Replicon | chromosome |
| Accession | NZ_CP021335 | ||
| Organism | Escherichia coli strain 95JB1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2254916..2255019 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2254915..2255149 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EC95JB1_RS12160 | 2251863..2252915 | + | 1053 | WP_001004413.1 | recombinase RecT | - |
| EC95JB1_RS12165 | 2252979..2253173 | + | 195 | WP_010989194.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| EC95JB1_RS12170 | 2253166..2253354 | + | 189 | WP_024177035.1 | DUF1187 family protein | - |
| - | 2253172..2253350 | - | 179 | NuclAT_0 | - | - |
| - | 2253172..2253350 | - | 179 | NuclAT_0 | - | - |
| - | 2253172..2253350 | - | 179 | NuclAT_0 | - | - |
| - | 2253172..2253350 | - | 179 | NuclAT_0 | - | - |
| EC95JB1_RS12175 | 2253461..2253742 | + | 282 | WP_005127484.1 | excisionase | - |
| EC95JB1_RS12180 | 2253708..2254784 | + | 1077 | WP_001189085.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2254915..2255149 | + | 235 | - | - | Antitoxin |
| - | 2254916..2255019 | - | 104 | - | - | Toxin |
| EC95JB1_RS12185 | 2255177..2255518 | - | 342 | WP_000976491.1 | YebY family protein | - |
| EC95JB1_RS12190 | 2255531..2256403 | - | 873 | WP_000879274.1 | copper homeostasis membrane protein CopD | - |
| EC95JB1_RS12195 | 2256407..2256781 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| EC95JB1_RS12200 | 2256920..2257150 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| EC95JB1_RS12205 | 2257252..2257908 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| EC95JB1_RS12210 | 2257932..2258594 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleC | 2184293..2258594 | 74301 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T76474 NZ_CP021335:c2255019-2254916 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT76474 NZ_CP021335:2254915-2255149 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
