Detailed information of TA system TA076444

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-YefM
• Location: 1050975..1051477
• Replicon: chromosome
• Accession: NZ_CP021323
• Organism: Kushneria konosiri strain X49

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: B9G99_RS04935
• Protein ID: WP_086621003.1
• Coordinates: 1050975..1051229 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: B9G99_RS04940
• Protein ID: WP_086621004.1
• Coordinates: 1051226..1051477 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B9G99_RS04915	1046674..1047456	-	783	WP_086620999.1	carbon-nitrogen hydrolase family protein	-
B9G99_RS04920	1047815..1048843	-	1029	WP_086621000.1	hypothetical protein	-
B9G99_RS04925	1049023..1049742	-	720	WP_086621001.1	FRG domain-containing protein	-
B9G99_RS04930	1049844..1050350	-	507	WP_086621002.1	hypothetical protein	-
B9G99_RS04935	1050975..1051229	-	255	WP_086621003.1	Txe/YoeB family addiction module toxin	Toxin
B9G99_RS04940	1051226..1051477	-	252	WP_086621004.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
B9G99_RS04945	1051533..1051919	-	387	WP_086621005.1	DUF2007 domain-containing protein	-
B9G99_RS04950	1052029..1054146	-	2118	WP_086621006.1	ferric-rhodotorulic acid/ferric-coprogen receptor FhuE	-
B9G99_RS04955	1054372..1055445	+	1074	WP_086621007.1	biotin synthase BioB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (2-74)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10143.60 Da
• Isoelectric Point: 8.8642

>T76444 WP_086621003.1 NZ_CP021323:c1051229-1050975 [Kushneria konosiri]
VKRLFSENAWEDDLYWQTTDKKVLGRINKLIREIQCQPFEGMGKPEPLKHGFSGYWSRRINDEHRIVYKVTDDALMIAQL
RYHY

Nucleotide

• Length: 255 bp

>T76444 NZ_CP021323:c1051229-1050975 [Kushneria konosiri]
GTGAAGCGCCTGTTTTCCGAGAATGCCTGGGAGGATGACCTGTACTGGCAGACAACCGACAAGAAGGTGCTCGGGCGCAT
CAACAAACTGATCAGGGAAATCCAGTGCCAGCCATTTGAAGGTATGGGCAAGCCGGAGCCGCTCAAACACGGCTTTTCAG
GTTATTGGTCCCGGCGAATCAACGACGAGCATCGAATTGTTTATAAAGTGACAGACGACGCGCTGATGATTGCGCAGCTT
CGATATCACTATTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9237.54 Da
• Isoelectric Point: 4.7954

>AT76444 WP_086621004.1 NZ_CP021323:c1051477-1051226 [Kushneria konosiri]
VDAISYTAARSQLSKTMEQVCEDHAPIVITRSKAPSVVMLSLEDYEALQETAYLLRSPKNARRLLESMAELEQGDGQKKA
LLE

Nucleotide

• Length: 252 bp

>AT76444 NZ_CP021323:c1051477-1051226 [Kushneria konosiri]
GTGGATGCCATCAGCTATACCGCTGCCAGAAGCCAGCTGTCCAAAACCATGGAACAGGTGTGTGAAGACCACGCGCCCAT
CGTCATCACGCGCAGCAAGGCGCCTTCGGTGGTCATGCTCTCGCTGGAAGACTACGAGGCCCTGCAGGAAACCGCCTATC
TTCTGCGCTCACCCAAAAACGCCCGCCGCCTGCTGGAGTCCATGGCCGAGCTGGAGCAAGGCGACGGTCAGAAAAAGGCG
CTTCTTGAGTGA