Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 514964..515441 Replicon chromosome
Accession NZ_CP021255
Organism Desulfobulbus oralis strain HOT041/ORNL

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag CAY53_RS02085 Protein ID WP_104935724.1
Coordinates 515172..515441 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag CAY53_RS02080 Protein ID WP_104935723.1
Coordinates 514964..515188 (+) Length 75 a.a.

Genomic Context

CAY53_RS02055CAY53_RS02060CAY53_RS02075CAY53_RS02080CAY53_RS02085CAY53_RS02090CAY53_RS02095CAY53_RS02050CAY53_RS12440CAY53_RS12445CAY53_RS02105CAY53_RS02110
Location: 511020..511759 (740 bp)
Type: Others
Protein ID: Protein_411
Location: 512183..513439 (1257 bp)
Type: Others
Protein ID: WP_104935672.1
Location: 513735..514591 (857 bp)
Type: Others
Protein ID: Protein_413
Location: 514964..515188 (225 bp)
Type: Antitoxin
Protein ID: WP_104935723.1
Location: 515172..515441 (270 bp)
Type: Toxin
Protein ID: WP_104935724.1
Location: 515478..515831 (354 bp)
Type: Others
Protein ID: WP_104935725.1
Location: 515828..518137 (2310 bp)
Type: Others
Protein ID: WP_104935726.1
Location: 510113..510556 (444 bp)
Type: Others
Protein ID: WP_104935618.1
Location: 518205..518618 (414 bp)
Type: Others
Protein ID: WP_146106369.1
Location: 518661..519260 (600 bp)
Type: Others
Protein ID: WP_146106370.1
Location: 519235..519474 (240 bp)
Type: Others
Protein ID: WP_017866015.1
Location: 519505..520053 (549 bp)
Type: Others
Protein ID: WP_104935728.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CAY53_RS02050510113..510556-444WP_104935618.1IS200/IS605 family transposase-
CAY53_RS02055511020..511759+740Protein_411IS5 family transposase-
CAY53_RS02060512183..513439+1257WP_104935672.1ISL3 family transposase-
CAY53_RS02075513735..514591+857Protein_413site-specific integrase-
CAY53_RS02080514964..515188+225WP_104935723.1TraY domain-containing proteinAntitoxin
CAY53_RS02085515172..515441+270WP_104935724.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CAY53_RS02090515478..515831+354WP_104935725.1conjugal transfer protein TraJ-
CAY53_RS02095515828..518137+2310WP_104935726.1relaxase/mobilization nuclease domain-containing protein-
CAY53_RS12440518205..518618-414WP_146106369.1hypothetical protein-
CAY53_RS12445518661..519260-600WP_146106370.1hypothetical protein-
CAY53_RS02105519235..519474-240WP_017866015.1hypothetical protein-
CAY53_RS02110519505..520053-549WP_104935728.1tyrosine-type recombinase/integrase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--514964..5200535089


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin

Relaxosome protein TraY

(4-49)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10363.07 Da        Isoelectric Point: 10.2161

>T76338 WP_104935724.1 NZ_CP021255:515172-515441 [Desulfobulbus oralis]
MGWKIELARAAERDLDKLDPQVARRILVFLHGRLAELDDPRSIGEPLKGSKLGEFWKYRVGDYRVISSIEDKVLTILVVR
IGNRREVYR

Download         Length: 270 bp

>T76338 NZ_CP021255:515172-515441 [Desulfobulbus oralis]
ATGGGCTGGAAAATTGAGCTTGCCCGCGCTGCAGAACGTGATTTGGATAAACTCGATCCTCAGGTGGCCAGACGTATTCT
TGTTTTTCTGCATGGCCGTCTGGCTGAACTGGACGACCCACGCAGTATCGGTGAGCCACTCAAAGGATCGAAGCTGGGTG
AATTCTGGAAGTACCGCGTCGGTGATTACAGGGTAATCAGCAGCATCGAGGACAAGGTGCTGACAATCCTCGTTGTGAGA
ATTGGCAATCGTCGAGAGGTCTACAGATAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8402.63 Da        Isoelectric Point: 4.4633

>AT76338 WP_104935723.1 NZ_CP021255:514964-515188 [Desulfobulbus oralis]
MLAIRLPAEIEARLDAMAKATGRTKTFYARQAILEYLDDLEDLYLAEQRLSEIRTGASEVVALEEVVKRYGLEN

Download         Length: 225 bp

>AT76338 NZ_CP021255:514964-515188 [Desulfobulbus oralis]
ATGCTCGCAATCAGACTGCCCGCTGAGATAGAAGCCCGGCTTGACGCCATGGCAAAGGCCACTGGCCGAACCAAAACATT
CTATGCCCGGCAAGCCATTCTCGAATACCTGGATGATCTTGAAGACCTGTATCTGGCTGAGCAACGATTGAGCGAGATCA
GAACCGGAGCGTCGGAGGTTGTGGCTCTTGAGGAAGTGGTGAAGCGCTATGGGCTGGAAAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References