Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3645214..3645485 Replicon chromosome
Accession NZ_CP021175
Organism Escherichia coli strain 5CRE51

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3645344..3645447 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3645214..3645485 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CA593_RS18730 3641769..3642431 - 663 WP_000944256.1 exodeoxyribonuclease X -
CA593_RS18735 3642455..3643111 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CA593_RS18740 3643213..3643443 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CA593_RS18745 3643582..3643956 + 375 WP_000168747.1 CopC domain-containing protein YobA -
CA593_RS18750 3643960..3644832 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
CA593_RS18755 3644845..3645186 + 342 WP_000976476.1 YebY family protein -
- 3645214..3645485 - 272 - - Antitoxin
- 3645344..3645447 + 104 - - Toxin
CA593_RS18760 3645582..3646238 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
CA593_RS18765 3646239..3646430 - 192 WP_000457842.1 YebW family protein -
CA593_RS18770 3646535..3646771 - 237 WP_001295499.1 DUF1480 family protein -
CA593_RS18775 3646889..3648328 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T76164 NZ_CP021175:3645344-3645447 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT76164 NZ_CP021175:c3645485-3645214 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATAGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References