Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1865192..1865337 Replicon chromosome
Accession NZ_CP021165
Organism Klebsiella pneumoniae strain 203

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1865228..1865330 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1865192..1865337 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BH367_RS09305 1860322..1862382 + 2061 WP_004151449.1 oligopeptidase B -
BH367_RS09310 1862386..1863045 - 660 WP_002911407.1 exodeoxyribonuclease X -
BH367_RS09315 1863124..1863354 - 231 WP_048254886.1 DNA polymerase III subunit theta -
BH367_RS09320 1863467..1863841 + 375 WP_004151448.1 CopC domain-containing protein YobA -
BH367_RS09325 1863845..1864714 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
BH367_RS09330 1864731..1865069 + 339 WP_016529031.1 YebY family protein -
- 1865192..1865337 - 146 - - Antitoxin
- 1865228..1865330 + 103 - - Toxin
BH367_RS27455 1865705..1865848 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
BH367_RS09340 1865953..1866921 - 969 WP_004151446.1 VirK/YbjX family protein -
BH367_RS09345 1867078..1867731 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
BH367_RS09350 1867728..1867919 - 192 WP_002911395.1 YebW family protein -
BH367_RS09355 1868017..1868256 - 240 WP_002911393.1 YebV family protein -
BH367_RS09360 1868372..1869805 - 1434 WP_071081310.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T76095 NZ_CP021165:1865228-1865330 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT76095 NZ_CP021165:c1865337-1865192 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References