Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1922378..1922518 Replicon chromosome
Accession NZ_CP021164
Organism Serratia marcescens strain 332

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1922422..1922518 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1922378..1922518 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B1A42_RS09220 1917576..1918001 + 426 WP_033653830.1 RNA polymerase-binding protein DksA -
B1A42_RS09225 1918196..1919149 + 954 WP_110158631.1 prolyl aminopeptidase -
B1A42_RS09230 1919183..1919413 - 231 WP_049272619.1 DNA polymerase III subunit theta -
B1A42_RS09235 1919758..1920276 + 519 WP_038875847.1 non-heme ferritin -
B1A42_RS09240 1920569..1920985 + 417 WP_046686875.1 CopC domain-containing protein YobA -
B1A42_RS09245 1920988..1921869 + 882 WP_110157676.1 copper homeostasis membrane protein CopD -
B1A42_RS09250 1921939..1922280 + 342 WP_061872086.1 YebY family protein -
- 1922378..1922518 - 141 - - Antitoxin
- 1922422..1922518 + 97 - - Toxin
B1A42_RS09255 1922570..1923091 - 522 WP_110157677.1 tyrosine-type recombinase/integrase -
B1A42_RS09260 1923005..1923451 + 447 WP_162598272.1 hypothetical protein -
B1A42_RS24600 1923802..1924416 + 615 WP_162598273.1 hypothetical protein -
B1A42_RS09270 1924704..1925774 - 1071 WP_077791528.1 AAA family ATPase -
B1A42_RS09275 1926069..1926296 + 228 WP_110157680.1 holin -
B1A42_RS09280 1926301..1926764 + 464 Protein_1770 lysozyme -
B1A42_RS09285 1926761..1927133 + 373 Protein_1771 DUF2570 family protein -
B1A42_RS24605 1927018..1927287 + 270 WP_162531731.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1913696..1929282 15586


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T76078 NZ_CP021164:1922422-1922518 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT76078 NZ_CP021164:c1922518-1922378 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References