Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 572133..572908 Replicon chromosome
Accession NZ_CP021158
Organism Burkholderia glumae strain 411gr-6

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag B7760_RS19210 Protein ID WP_017423245.1
Coordinates 572411..572908 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag B7760_RS19205 Protein ID WP_161521884.1
Coordinates 572133..572414 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7760_RS19205 (B7760_03840) 572133..572414 + 282 WP_161521884.1 DUF1778 domain-containing protein Antitoxin
B7760_RS19210 (B7760_03841) 572411..572908 + 498 WP_017423245.1 GNAT family N-acetyltransferase Toxin
B7760_RS30705 573198..573470 + 273 WP_252979779.1 ProQ/FINO family protein -
B7760_RS30710 573830..574378 + 549 Protein_508 RHS domain-containing protein -
B7760_RS19225 574779..575063 + 285 WP_153478924.1 hypothetical protein -
B7760_RS19230 (B7760_03843) 575186..575731 + 546 Protein_510 IS3 family transposase -
B7760_RS19235 (B7760_03844) 575984..577333 - 1350 WP_161521886.1 allantoin permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 559770..583406 23636
- flank IS/Tn - - 575213..575755 542


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-144)

Antitoxin

Vibrio phage ICP1, Orf50

(5-91)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17606.19 Da        Isoelectric Point: 9.6894

>T76058 WP_017423245.1 NZ_CP021158:572411-572908 [Burkholderia glumae]
MTGWRAPEPLSDAHGLDDFDSGVASLDTWLKRRALANQRSGASRTFVATRDGRVGAYYALASGAVTLEVAPGRFRRNMPD
PIPVVVLGRLAVDRAHQGIGVGRALVRDAGLRVLHAAAAIGIRSLIVHALSDSAKAFYERVGFEASPLDPMLLLITLADL
EHALS

Download         Length: 498 bp

>T76058 NZ_CP021158:572411-572908 [Burkholderia glumae]
ATGACGGGCTGGCGCGCGCCCGAACCGCTCAGCGACGCGCACGGGCTCGACGATTTCGATTCCGGCGTCGCGAGCCTCGA
CACGTGGCTCAAACGCCGTGCACTGGCCAATCAGCGTAGCGGTGCGTCGCGGACCTTTGTGGCGACGCGAGACGGTCGAG
TGGGGGCGTACTACGCACTCGCGTCCGGCGCGGTTACGCTCGAGGTCGCACCGGGCCGCTTCCGGCGCAACATGCCCGAT
CCGATACCGGTGGTTGTGCTCGGGCGTCTCGCCGTCGATCGCGCCCATCAGGGCATTGGGGTTGGGCGTGCGCTGGTACG
CGATGCGGGCTTGCGTGTGTTGCACGCCGCAGCGGCCATCGGGATTCGCAGCCTGATCGTGCATGCACTCTCGGACTCGG
CCAAGGCGTTCTATGAGCGGGTCGGCTTTGAGGCGTCGCCGCTCGATCCGATGCTGCTCCTGATCACGCTGGCCGACCTC
GAGCACGCCTTGTCATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10226.50 Da        Isoelectric Point: 5.0477

>AT76058 WP_161521884.1 NZ_CP021158:572133-572414 [Burkholderia glumae]
MASTTPRDTLNLRIRPDDRSLIDRAAAAAHKTRTDFVLDAARAAAEQTLLDQVVLSAEPQAYAAFLARLDEPVQPNEALR
QTMQTRAPWDPAA

Download         Length: 282 bp

>AT76058 NZ_CP021158:572133-572414 [Burkholderia glumae]
ATGGCCTCGACCACCCCGCGCGACACCCTGAACTTACGCATTCGTCCTGACGATCGCAGCTTGATTGACCGCGCCGCAGC
GGCCGCCCACAAAACGCGTACCGACTTCGTCCTGGACGCAGCGCGGGCCGCCGCCGAACAGACCTTGCTCGACCAGGTTG
TTCTGAGCGCCGAGCCGCAGGCCTACGCGGCCTTCCTGGCGCGCCTGGACGAGCCGGTCCAACCGAACGAGGCATTGCGC
CAGACCATGCAGACACGCGCGCCTTGGGACCCCGCTGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References