Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 501226..501460 Replicon chromosome
Accession NZ_CP021144
Organism Shigella sonnei strain 2015AM-1099

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 501356..501459 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 501226..501460 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9127_RS02875 497780..498442 - 663 WP_000944256.1 exodeoxyribonuclease X -
B9127_RS02880 498466..499122 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
B9127_RS02885 499225..499455 - 231 WP_000916763.1 DNA polymerase III subunit theta -
B9127_RS02890 499594..499968 + 375 WP_000168735.1 CopC domain-containing protein YobA -
B9127_RS02895 499972..500844 + 873 WP_000879296.1 copper homeostasis membrane protein CopD -
B9127_RS02900 500857..501198 + 342 WP_000976476.1 YebY family protein -
- 501226..501460 - 235 - - Antitoxin
- 501356..501459 + 104 - - Toxin
B9127_RS02905 501591..502667 - 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
B9127_RS02910 502704..502949 - 246 Protein_521 IS1 family transposase -
B9127_RS02920 504283..504737 - 455 Protein_523 IS1-like element IS1A family transposase -
B9127_RS02925 504766..505026 - 261 WP_077447296.1 excisionase -
B9127_RS02930 505171..506327 + 1157 WP_087879964.1 IS3-like element IS600 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T76033 NZ_CP021144:501356-501459 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT76033 NZ_CP021144:c501460-501226 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References