Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 1007244..1008350 Replicon chromosome
Accession NZ_CP021138
Organism Sulfuriferula sp. AH1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag CAP31_RS05255 Protein ID WP_087446575.1
Coordinates 1007604..1008350 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag CAP31_RS05250 Protein ID WP_087446574.1
Coordinates 1007244..1007603 (+) Length 120 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAP31_RS05235 1002963..1004357 + 1395 WP_087446571.1 aspartate aminotransferase family protein -
CAP31_RS05240 1004338..1005561 + 1224 WP_087446572.1 RimK family alpha-L-glutamate ligase -
CAP31_RS05245 1005545..1007098 + 1554 WP_157662658.1 hypothetical protein -
CAP31_RS05250 1007244..1007603 + 360 WP_087446574.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
CAP31_RS05255 1007604..1008350 + 747 WP_087446575.1 RES family NAD+ phosphorylase Toxin
CAP31_RS05260 1008431..1009633 - 1203 WP_087446576.1 ammonium transporter -
CAP31_RS05265 1009830..1010633 - 804 WP_087446577.1 twin-arginine translocase subunit TatC -
CAP31_RS05270 1010630..1011052 - 423 WP_087446578.1 Sec-independent protein translocase protein TatB -
CAP31_RS05275 1011061..1011273 - 213 WP_087446579.1 Sec-independent protein translocase subunit TatA -
CAP31_RS05280 1011286..1011624 - 339 WP_087446580.1 histidine triad nucleotide-binding protein -
CAP31_RS05285 1011621..1011944 - 324 WP_087446581.1 phosphoribosyl-ATP diphosphatase -
CAP31_RS05290 1011941..1012336 - 396 WP_087446582.1 phosphoribosyl-AMP cyclohydrolase -
CAP31_RS05295 1012333..1013094 - 762 WP_087446583.1 imidazole glycerol phosphate synthase subunit HisF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(57-205)

Antitoxin

(70-117)


Sequences


Toxin        


Download         Length: 249 a.a.        Molecular weight: 27484.47 Da        Isoelectric Point: 6.3445

>T76031 WP_087446575.1 NZ_CP021138:1007604-1008350 [Sulfuriferula sp. AH1]
VVDWSLCLAEAELRSLSGVLLRLVESQEQVATNQLVSSLERQLVLEDMLEATKPRLRAETRGLHYLLATPFRYPPLKHGS
RFSTRNAPSLFYGALETGTVLAEAAYYRFLFWYGMATPPAGKLDTQHTLFGAEYRTGKGLQLQALPFASYREVLTSPSDY
GPTQVLGAEMRTAGVEAFEFISVRDPEGGINVALFTPAALGAKAPVFQEPWLCEVTAERVRFHAAHSRTLYTFPIEVFLV
EGKLPQAA

Download         Length: 747 bp

>T76031 NZ_CP021138:1007604-1008350 [Sulfuriferula sp. AH1]
GTGGTCGATTGGTCTCTTTGTCTGGCAGAAGCCGAATTGCGCAGTCTGTCAGGCGTGCTGTTGCGGCTGGTAGAGAGCCA
GGAGCAGGTTGCGACCAACCAGCTGGTCAGTTCGCTGGAGCGGCAATTGGTGCTGGAGGATATGCTGGAGGCGACAAAAC
CGCGTCTGCGTGCGGAAACCAGGGGGCTTCACTACCTGCTGGCGACACCGTTTCGCTATCCGCCATTGAAACACGGTTCG
CGTTTCAGCACGCGTAACGCACCAAGCCTGTTTTACGGGGCGCTGGAAACCGGCACGGTGCTGGCAGAAGCTGCCTATTA
CCGATTCCTGTTCTGGTACGGCATGGCGACGCCGCCTGCGGGCAAACTTGATACGCAGCATACCCTGTTTGGCGCCGAAT
ACCGCACAGGGAAGGGGCTGCAGCTACAAGCCTTGCCGTTCGCAAGTTATCGTGAAGTGCTGACCAGTCCATCGGATTAC
GGACCGACTCAGGTGCTCGGTGCCGAGATGCGCACAGCCGGGGTCGAGGCATTCGAATTCATCTCTGTGCGCGATCCGGA
AGGCGGCATCAATGTCGCTTTATTCACGCCTGCGGCGCTAGGCGCAAAGGCTCCGGTGTTTCAGGAACCGTGGTTATGTG
AGGTAACTGCAGAACGGGTTCGTTTTCATGCTGCGCATAGTCGCACGCTGTACACGTTTCCCATCGAGGTGTTCCTGGTT
GAGGGTAAATTACCGCAAGCTGCCTGA

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13072.02 Da        Isoelectric Point: 6.7179

>AT76031 WP_087446574.1 NZ_CP021138:1007244-1007603 [Sulfuriferula sp. AH1]
MSLALVPDTEKSSVLTEALANAGKHLGMNQSDLGEVIGKNRTAISRGDIDPDSKAGELALLFIRCYRSLFVLVGGDFQQM
RHWMQTENLHTGGIPREQIKSVQGLTTVLEYLDAMRGKL

Download         Length: 360 bp

>AT76031 NZ_CP021138:1007244-1007603 [Sulfuriferula sp. AH1]
ATGAGTTTGGCGCTTGTACCCGATACTGAAAAATCCAGTGTCCTCACAGAAGCTTTGGCTAATGCCGGCAAGCACTTGGG
TATGAATCAGTCAGACCTCGGCGAAGTGATAGGCAAAAATCGCACTGCGATCAGCCGCGGCGACATCGACCCTGACAGCA
AGGCCGGGGAGCTGGCGTTGTTGTTCATCCGCTGTTATCGCTCGCTTTTTGTGCTGGTCGGAGGGGATTTTCAGCAGATG
CGGCACTGGATGCAGACTGAAAACCTGCATACAGGCGGCATTCCGCGCGAGCAGATCAAAAGCGTACAAGGCCTGACCAC
GGTGCTGGAATATCTGGATGCCATGCGGGGCAAGCTGTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References