Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 779228..779792 Replicon chromosome
Accession NZ_CP021138
Organism Sulfuriferula sp. AH1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CAP31_RS04120 Protein ID WP_087446378.1
Coordinates 779481..779792 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CAP31_RS04115 Protein ID WP_087446377.1
Coordinates 779228..779479 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAP31_RS04085 776118..776519 - 402 WP_157662647.1 hypothetical protein -
CAP31_RS04090 776636..776848 + 213 WP_157662648.1 hypothetical protein -
CAP31_RS04095 776823..777824 + 1002 WP_087446374.1 NAD(P)-dependent alcohol dehydrogenase -
CAP31_RS04100 777936..778199 - 264 WP_087446375.1 Txe/YoeB family addiction module toxin -
CAP31_RS04105 778196..778438 - 243 WP_087448247.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
CAP31_RS04110 778537..779064 - 528 WP_087446376.1 transposase -
CAP31_RS04115 779228..779479 + 252 WP_087446377.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CAP31_RS04120 779481..779792 + 312 WP_087446378.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CAP31_RS04125 779919..780344 + 426 WP_087446379.1 hypothetical protein -
CAP31_RS04135 781048..781350 - 303 WP_087446381.1 DUF2288 domain-containing protein -
CAP31_RS04140 781421..782872 - 1452 WP_087446382.1 DNA recombination protein RmuC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(10-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-74)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11984.09 Da        Isoelectric Point: 9.9384

>T76030 WP_087446378.1 NZ_CP021138:779481-779792 [Sulfuriferula sp. AH1]
MAEQYKYKLKFVPDALGEWNRLDGSVKEPLRKLLKKRLNEPFMPGSELHGELRNCYKIKLLKQGYRLVYVVENDELVVLV
LAVDKREDATVYTSATARLKTKI

Download         Length: 312 bp

>T76030 NZ_CP021138:779481-779792 [Sulfuriferula sp. AH1]
ATGGCCGAACAATATAAATACAAATTAAAGTTCGTGCCTGATGCGCTGGGAGAATGGAATCGGCTTGATGGTTCTGTTAA
AGAGCCATTACGCAAATTGCTGAAAAAGCGGTTGAATGAGCCTTTCATGCCGGGTTCGGAATTGCATGGCGAGTTGCGGA
ATTGTTATAAAATCAAGTTGTTAAAGCAGGGTTACCGGCTGGTTTATGTAGTGGAAAATGATGAGTTGGTGGTGCTTGTG
CTGGCAGTGGACAAACGTGAAGATGCTACGGTTTACACTTCGGCAACGGCGCGGCTGAAAACTAAAATCTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9445.03 Da        Isoelectric Point: 4.9681

>AT76030 WP_087446377.1 NZ_CP021138:779228-779479 [Sulfuriferula sp. AH1]
MQTIFTDLTISMSDFKKNPAKVLREAGQKPVAVLNHNKPAFYMVDPQMFELLIEQLADNQLMPLLQARMAQRANAVEVNI
DEI

Download         Length: 252 bp

>AT76030 NZ_CP021138:779228-779479 [Sulfuriferula sp. AH1]
ATGCAAACCATCTTTACCGATCTGACCATCAGTATGTCGGACTTCAAGAAAAACCCGGCCAAGGTGCTGCGCGAGGCAGG
CCAAAAACCGGTTGCCGTGCTCAACCACAACAAACCGGCGTTTTACATGGTTGATCCGCAGATGTTTGAGCTGCTCATTG
AGCAGCTGGCTGATAATCAGCTGATGCCGTTGTTGCAAGCACGTATGGCGCAACGTGCCAACGCAGTGGAAGTGAACATC
GACGAGATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References