Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 213348..214015 Replicon plasmid pRetKim5d
Accession NZ_CP021128
Organism Rhizobium sp. Kim5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KIM5_RS31185 Protein ID WP_077994590.1
Coordinates 213348..213791 (-) Length 148 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KIM5_RS31190 Protein ID WP_183758872.1
Coordinates 213788..214015 (-) Length 76 a.a.

Genomic Context

KIM5_RS31160KIM5_RS31165KIM5_RS31170KIM5_RS31175KIM5_RS31200KIM5_RS31205KIM5_RS31210KIM5_RS31215KIM5_RS31220KIM5_RS31180KIM5_RS31185KIM5_RS31190KIM5_RS31195
Location: 209100..210467 (1368 bp)
Type: Others
Protein ID: WP_086156702.1
Location: 210537..211307 (771 bp)
Type: Others
Protein ID: WP_077994581.1
Location: 211486..212496 (1011 bp)
Type: Others
Protein ID: WP_077994582.1
Location: 212534..212851 (318 bp)
Type: Others
Protein ID: WP_086156703.1
Location: 214680..215219 (540 bp)
Type: Others
Protein ID: WP_077994595.1
Location: 215223..215882 (660 bp)
Type: Others
Protein ID: WP_086156704.1
Location: 215879..216178 (300 bp)
Type: Others
Protein ID: WP_009986199.1
Location: 216184..216522 (339 bp)
Type: Others
Protein ID: WP_009986201.1
Location: 216515..218881 (2367 bp)
Type: Others
Protein ID: WP_086156705.1
Location: 212896..213339 (444 bp)
Type: Others
Protein ID: Protein_209
Location: 213348..213791 (444 bp)
Type: Toxin
Protein ID: WP_077994590.1
Location: 213788..214015 (228 bp)
Type: Antitoxin
Protein ID: WP_183758872.1
Location: 214216..214581 (366 bp)
Type: Others
Protein ID: WP_077994592.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KIM5_RS31160209100..210467+1368WP_086156702.1four-carbon acid sugar kinase family protein-
KIM5_RS31165210537..211307+771WP_077994581.13-oxoacyl-ACP reductase FabG-
KIM5_RS31170211486..212496+1011WP_077994582.12-keto-3-deoxygluconate permease-
KIM5_RS31175212534..212851+318WP_086156703.1LysR family transcriptional regulator-
KIM5_RS31180212896..213339-444Protein_209polyhydroxybutyrate depolymerase-
KIM5_RS31185213348..213791-444WP_077994590.1PIN domain-containing proteinToxin
KIM5_RS31190213788..214015-228WP_183758872.1CopG family transcriptional regulatorAntitoxin
KIM5_RS31195214216..214581-366WP_077994592.1MarR family transcriptional regulator-
KIM5_RS31200214680..215219+540WP_077994595.1hypothetical protein-
KIM5_RS31205215223..215882+660WP_086156704.1transglycosylase SLT domain-containing protein-
KIM5_RS31210215879..216178+300WP_009986199.1TrbC/VirB2 family protein-
KIM5_RS31215216184..216522+339WP_009986201.1type IV secretion system protein VirB3-
KIM5_RS31220216515..218881+2367WP_086156705.1VirB4 family type IV secretion system protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideConjugative plasmid--1..684601684601


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(2-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 148 a.a.        Molecular weight: 15557.83 Da        Isoelectric Point: 7.4219

>T76022 WP_077994590.1 NZ_CP021128:c213791-213348 [Rhizobium sp. Kim5]
VTFLLDVNVLIALIDPGHVAHDDAHEWFAAIGQTAWATCPITENGVLRIVGNPKYPNSPGSPALVMEIVRKLRSLPGHSF
WPDDVSLVGSGDIAPTKILTPGQVTDTYLLALAKARGGQLATFDRKLSAAAVTRGNSALHPIATSRS

Download         Length: 444 bp

>T76022 NZ_CP021128:c213791-213348 [Rhizobium sp. Kim5]
GTGACTTTCCTGCTCGACGTCAATGTGCTGATTGCCTTAATCGATCCGGGCCATGTAGCTCATGATGATGCGCACGAATG
GTTCGCTGCGATCGGTCAGACCGCGTGGGCTACCTGCCCCATTACCGAAAATGGTGTCCTCCGGATTGTCGGCAATCCCA
AATATCCCAACTCTCCCGGTTCACCGGCACTCGTGATGGAGATCGTCCGCAAATTGCGGTCACTCCCCGGTCACAGTTTT
TGGCCGGACGATGTCAGCCTTGTCGGGTCAGGCGATATCGCTCCCACGAAAATCCTAACACCGGGACAGGTAACTGACAC
CTACCTGCTTGCGCTAGCCAAGGCGCGTGGTGGCCAGCTGGCGACATTCGATCGCAAGCTGTCAGCGGCAGCGGTTACAA
GGGGCAATTCTGCCTTGCACCCGATCGCCACGAGCAGATCGTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8211.41 Da        Isoelectric Point: 9.1311

>AT76022 WP_183758872.1 NZ_CP021128:c214015-213788 [Rhizobium sp. Kim5]
MRTTLAIDDDVLIAAKAMATQQHRSVGEVISELARRSLRRPPSSGERNGIPLLSARPEAPPVTLEIVNALRDERP

Download         Length: 228 bp

>AT76022 NZ_CP021128:c214015-213788 [Rhizobium sp. Kim5]
ATGAGAACGACCTTGGCAATCGACGACGATGTCCTGATCGCCGCAAAAGCGATGGCAACCCAGCAGCACCGGAGCGTCGG
CGAGGTCATTTCTGAGCTGGCGAGACGTTCTCTGCGCCGACCGCCCAGCAGCGGTGAGCGCAACGGCATTCCTCTCCTGT
CAGCTCGGCCGGAAGCGCCGCCAGTGACGCTCGAAATCGTCAACGCCTTGCGTGACGAACGGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References