Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 950928..951646 Replicon chromosome
Accession NZ_CP021124
Organism Rhizobium sp. Kim5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KIM5_RS04780 Protein ID WP_009996200.1
Coordinates 950928..951386 (-) Length 153 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A060I3H0
Locus tag KIM5_RS04785 Protein ID WP_009996202.1
Coordinates 951383..951646 (-) Length 88 a.a.

Genomic Context

KIM5_RS33535KIM5_RS04770KIM5_RS04775KIM5_RS04790KIM5_RS04795KIM5_RS04760KIM5_RS04765KIM5_RS04780KIM5_RS04785KIM5_RS04800
Location: 946038..946670 (633 bp)
Type: Others
Protein ID: WP_125461960.1
Location: 949054..949902 (849 bp)
Type: Others
Protein ID: WP_038687105.1
Location: 949917..950900 (984 bp)
Type: Others
Protein ID: WP_039623031.1
Location: 951999..954905 (2907 bp)
Type: Others
Protein ID: WP_086156068.1
Location: 955037..955666 (630 bp)
Type: Others
Protein ID: WP_038687111.1
Location: 946713..948350 (1638 bp)
Type: Others
Protein ID: WP_038687103.1
Location: 948422..948718 (297 bp)
Type: Others
Protein ID: WP_004675403.1
Location: 950928..951386 (459 bp)
Type: Toxin
Protein ID: WP_009996200.1
Location: 951383..951646 (264 bp)
Type: Antitoxin
Protein ID: WP_009996202.1
Location: 955953..956390 (438 bp)
Type: Others
Protein ID: WP_077991088.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KIM5_RS33535946038..946670+633WP_125461960.1hypothetical protein-
KIM5_RS04760946713..948350-1638WP_038687103.1chaperonin GroEL-
KIM5_RS04765948422..948718-297WP_004675403.1co-chaperone GroES-
KIM5_RS04770949054..949902+849WP_038687105.1TIGR01459 family HAD-type hydrolase-
KIM5_RS04775949917..950900+984WP_039623031.1bifunctional riboflavin kinase/FAD synthetase-
KIM5_RS04780950928..951386-459WP_009996200.1type II toxin-antitoxin system VapC family toxinToxin
KIM5_RS04785951383..951646-264WP_009996202.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
KIM5_RS04790951999..954905+2907WP_086156068.1isoleucine--tRNA ligase-
KIM5_RS04795955037..955666+630WP_038687111.1hypothetical protein-
KIM5_RS04800955953..956390-438WP_077991088.1nucleoside deaminase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(7-58)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17029.08 Da        Isoelectric Point: 5.2132

>T76016 WP_009996200.1 NZ_CP021124:c951386-950928 [Rhizobium sp. Kim5]
VIGWLLDTNVIAALINPNGAPSVKSWAAAQDENQMFISVLTLAEYDEGIENLPEDDRNRYRYIAARDALEERFSQRTLSL
SDAGVRHWGAISGRTKLRTGHTQPVIDTMLAATAIEHNLYLVTRNVKDTRFSGAAVFDPWTNDPDQFPLSRK

Download         Length: 459 bp

>T76016 NZ_CP021124:c951386-950928 [Rhizobium sp. Kim5]
GTGATCGGATGGCTGCTCGACACCAACGTCATTGCGGCGCTGATCAATCCGAACGGCGCGCCCTCCGTGAAGTCCTGGGC
TGCCGCGCAGGACGAGAACCAGATGTTCATCAGCGTGCTCACCCTCGCAGAATATGACGAAGGCATCGAAAACCTGCCTG
AAGACGACCGGAACCGCTATCGTTATATAGCGGCGCGCGACGCTCTGGAGGAGCGGTTCTCACAGCGTACTCTCTCGCTG
AGCGACGCGGGCGTCAGGCACTGGGGTGCTATTTCAGGGCGCACAAAACTGCGAACCGGACATACGCAACCGGTCATCGA
CACGATGCTGGCCGCCACCGCCATTGAGCACAATCTCTATCTGGTGACGCGGAACGTAAAGGATACGCGCTTCTCCGGCG
CGGCAGTTTTCGATCCGTGGACAAACGATCCGGATCAATTTCCATTGAGCCGGAAATAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10124.70 Da        Isoelectric Point: 8.5600

>AT76016 WP_009996202.1 NZ_CP021124:c951646-951383 [Rhizobium sp. Kim5]
MRKVIKQSWKLEDAKARFSEVVRRARSEGPQRVTVRGKDSVVIISVEELERLTKAEPKKPLVDFMESLALKELDLEREPD
YGRDVEL

Download         Length: 264 bp

>AT76016 NZ_CP021124:c951646-951383 [Rhizobium sp. Kim5]
ATGAGAAAAGTCATTAAGCAAAGCTGGAAGCTCGAGGACGCCAAAGCGCGCTTCAGCGAAGTCGTGCGCCGTGCCCGCAG
CGAAGGGCCACAGCGCGTCACAGTGCGCGGCAAAGACAGCGTCGTCATCATCAGCGTCGAAGAACTCGAACGGTTGACGA
AGGCCGAGCCCAAAAAGCCCCTGGTCGACTTCATGGAGAGCCTCGCTCTGAAAGAGCTCGATCTGGAGCGGGAGCCCGAT
TACGGGCGGGACGTCGAACTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A060I3H0

References