Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3147921..3148618 Replicon chromosome
Accession NZ_CP021112
Organism Pseudorhodoplanes sinuspersici strain RIPI110

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CAK95_RS15240 Protein ID WP_086088667.1
Coordinates 3148193..3148618 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CAK95_RS15235 Protein ID WP_086088666.1
Coordinates 3147921..3148196 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAK95_RS15220 3144883..3145584 - 702 WP_086088663.1 response regulator transcription factor -
CAK95_RS15225 3145954..3147279 + 1326 WP_086088664.1 flagellar protein export ATPase FliI -
CAK95_RS15230 3147376..3147795 + 420 WP_086088665.1 flagellar export protein FliJ -
CAK95_RS15235 3147921..3148196 + 276 WP_086088666.1 ribbon-helix-helix protein, CopG family Antitoxin
CAK95_RS15240 3148193..3148618 + 426 WP_086088667.1 type II toxin-antitoxin system VapC family toxin Toxin
CAK95_RS15245 3148707..3149468 + 762 WP_086088668.1 substrate-binding domain-containing protein -
CAK95_RS15250 3149570..3150427 + 858 WP_147413728.1 alpha/beta fold hydrolase -
CAK95_RS15255 3150499..3150906 - 408 WP_086088670.1 nucleoside diphosphate kinase regulator -
CAK95_RS15260 3151284..3151502 - 219 WP_086088671.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-133)

Antitoxin

Ribbon-helix-helix protein, CopG

(4-37)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 16079.45 Da        Isoelectric Point: 5.2147

>T76007 WP_086088667.1 NZ_CP021112:3148193-3148618 [Pseudorhodoplanes sinuspersici]
MILPDVNVLIYAFRRDAPDHALCKSWLENVAGGEASFGISPLTLSALVRITTNSRSYRMASTVEEAFRFCDALLQQPNCE
IVEPRARHWEIFKQLCVAADIRGPRVTDAWYAALAIEWGCEWITFDRDFARFPGLKWSLPE

Download         Length: 426 bp

>T76007 NZ_CP021112:3148193-3148618 [Pseudorhodoplanes sinuspersici]
ATGATCCTGCCGGACGTCAATGTGCTCATCTATGCATTCCGGCGCGATGCGCCCGATCATGCGCTGTGCAAATCCTGGCT
GGAAAACGTTGCAGGCGGTGAGGCCAGCTTTGGAATTTCGCCTTTGACGCTTTCCGCTCTCGTCCGCATCACAACGAATT
CTCGCTCATATCGGATGGCGAGCACAGTTGAAGAGGCATTTCGATTTTGCGATGCCCTTCTCCAACAGCCGAACTGTGAA
ATCGTCGAGCCCAGAGCGCGACATTGGGAGATCTTCAAGCAGCTTTGTGTTGCAGCCGACATTCGAGGCCCGCGCGTGAC
CGATGCATGGTATGCCGCCCTCGCGATAGAGTGGGGCTGCGAATGGATTACATTCGATCGCGATTTTGCGCGTTTTCCGG
GACTGAAATGGAGCCTGCCTGAGTAG

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10145.76 Da        Isoelectric Point: 10.2615

>AT76007 WP_086088666.1 NZ_CP021112:3147921-3148196 [Pseudorhodoplanes sinuspersici]
MTERTTVRLPEELLARAKRKAAAEGRTLTALIEDGLRRVVNETAAKPKKRRVSLPVSMATGGPMPGIDISDSAALQELED
LEYVERMKHFR

Download         Length: 276 bp

>AT76007 NZ_CP021112:3147921-3148196 [Pseudorhodoplanes sinuspersici]
ATGACCGAGCGCACGACAGTCAGGCTTCCGGAAGAGTTGCTGGCCCGCGCCAAGCGCAAGGCGGCGGCGGAGGGGCGGAC
GCTGACTGCGCTGATCGAGGATGGGTTGCGCCGGGTTGTCAACGAGACCGCTGCCAAGCCGAAGAAAAGACGCGTTTCGT
TGCCGGTCAGCATGGCGACGGGCGGGCCGATGCCCGGCATCGACATCAGCGATTCCGCTGCATTGCAGGAGCTTGAGGAT
CTCGAATACGTCGAGCGTATGAAGCACTTTCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References