Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 4797375..4797942 Replicon chromosome
Accession NZ_CP021111
Organism Bordetella genomosp. 13 strain AU7206

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CAL15_RS21625 Protein ID WP_086080374.1
Coordinates 4797658..4797942 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CAL15_RS21620 Protein ID WP_086081236.1
Coordinates 4797375..4797674 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAL15_RS21605 4792815..4793831 + 1017 WP_086081235.1 biotin-dependent carboxyltransferase family protein -
CAL15_RS21610 4793843..4794601 + 759 WP_086080373.1 LamB/YcsF family protein -
CAL15_RS21615 4796650..4797165 + 516 Protein_4260 IS3 family transposase -
CAL15_RS21620 4797375..4797674 + 300 WP_086081236.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CAL15_RS21625 4797658..4797942 + 285 WP_086080374.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CAL15_RS21630 4798576..4798881 - 306 WP_086081237.1 type I-E CRISPR-associated endoribonuclease Cas2 -
CAL15_RS21635 4798881..4799795 - 915 WP_198299097.1 type I-E CRISPR-associated endonuclease Cas1 -
CAL15_RS21640 4799804..4800415 - 612 WP_086080376.1 type I-E CRISPR-associated protein Cas6/Cse3/CasE -
CAL15_RS21645 4800390..4801067 - 678 WP_086080377.1 type I-E CRISPR-associated protein Cas5/CasD -
CAL15_RS21650 4801069..4802202 - 1134 WP_086080378.1 type I-E CRISPR-associated protein Cas7/Cse4/CasC -
CAL15_RS21655 4802218..4802760 - 543 WP_086080379.1 type I-E CRISPR-associated protein Cse2/CasB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4795612..4808245 12633
- flank IS/Tn - - 4796642..4796986 344


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-55)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10898.41 Da        Isoelectric Point: 4.7197

>T76004 WP_086080374.1 NZ_CP021111:4797658-4797942 [Bordetella genomosp. 13]
VPAKLEWKQIAQEEFLQHIDYIADESPDAAQKLKDEVESKVNELPEHPKLYRPGRVPGTREMVVRANYIVVYEEDETMVT
VLRVLHAAQLYPPQ

Download         Length: 285 bp

>T76004 NZ_CP021111:4797658-4797942 [Bordetella genomosp. 13]
GTGCCAGCAAAGCTTGAGTGGAAGCAGATTGCACAGGAGGAATTCCTTCAGCATATCGACTACATCGCGGACGAAAGTCC
CGATGCGGCGCAGAAACTGAAGGACGAAGTCGAATCCAAAGTCAACGAACTACCCGAGCATCCCAAGCTGTATCGTCCTG
GCCGTGTGCCAGGCACCCGCGAAATGGTGGTGCGCGCCAACTACATCGTCGTCTACGAAGAGGACGAAACCATGGTCACG
GTCTTGCGCGTGCTGCACGCGGCGCAACTTTATCCTCCGCAATAG

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10730.37 Da        Isoelectric Point: 10.1427

>AT76004 WP_086081236.1 NZ_CP021111:4797375-4797674 [Bordetella genomosp. 13]
MAHTSMLHIRVDDELKAAAAATLANVGLTVSDAVRILLTRIAKEGGLPAGLAVDPAAYDDWFRAKVQEAVDDKRPTTPHK
QVMDKAQAIIDRKRRASKA

Download         Length: 300 bp

>AT76004 NZ_CP021111:4797375-4797674 [Bordetella genomosp. 13]
ATGGCTCACACCTCAATGCTGCACATCCGTGTGGACGACGAACTGAAAGCCGCCGCTGCCGCTACGCTTGCCAACGTCGG
ACTGACGGTATCGGATGCCGTGCGTATCTTGCTAACCCGCATTGCCAAGGAAGGCGGGCTTCCCGCTGGTTTGGCCGTCG
ATCCCGCAGCCTATGACGATTGGTTTCGAGCCAAGGTACAGGAAGCCGTGGATGACAAGCGCCCCACAACGCCACACAAG
CAAGTGATGGACAAGGCACAGGCCATCATCGACAGGAAACGCCGTGCCAGCAAAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References