Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | FicTA/Fic(toxin) |
Location | 4222151..4222941 | Replicon | chromosome |
Accession | NZ_CP021111 | ||
Organism | Bordetella genomosp. 13 strain AU7206 |
Toxin (Protein)
Gene name | VbhT | Uniprot ID | - |
Locus tag | CAL15_RS19070 | Protein ID | WP_086079934.1 |
Coordinates | 4222151..4222756 (-) | Length | 202 a.a. |
Antitoxin (Protein)
Gene name | VbhA | Uniprot ID | - |
Locus tag | CAL15_RS19075 | Protein ID | WP_086081183.1 |
Coordinates | 4222753..4222941 (-) | Length | 63 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CAL15_RS19045 | 4217885..4218124 | + | 240 | WP_086079929.1 | Fis family transcriptional regulator | - |
CAL15_RS19050 | 4218141..4219730 | + | 1590 | WP_086079930.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
CAL15_RS19055 | 4219735..4220283 | + | 549 | WP_086079931.1 | crossover junction endodeoxyribonuclease RuvC | - |
CAL15_RS19060 | 4220444..4221016 | + | 573 | WP_086079932.1 | Holliday junction branch migration protein RuvA | - |
CAL15_RS19065 | 4221080..4222021 | - | 942 | WP_086079933.1 | complex I NDUFA9 subunit family protein | - |
CAL15_RS19070 | 4222151..4222756 | - | 606 | WP_086079934.1 | Fic/DOC family protein | Toxin |
CAL15_RS19075 | 4222753..4222941 | - | 189 | WP_086081183.1 | antitoxin VbhA family protein | Antitoxin |
CAL15_RS19080 | 4223091..4224059 | - | 969 | WP_086081184.1 | threo-3-hydroxy-L-aspartate ammonia-lyase | - |
CAL15_RS19085 | 4224245..4225321 | + | 1077 | WP_086079935.1 | Holliday junction branch migration DNA helicase RuvB | - |
CAL15_RS19090 | 4225959..4227773 | - | 1815 | WP_086079936.1 | DNA helicase RecQ | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 202 a.a. Molecular weight: 22399.22 Da Isoelectric Point: 7.1867
>T76003 WP_086079934.1 NZ_CP021111:c4222756-4222151 [Bordetella genomosp. 13]
MKYAGDRGDPYLYSGTEVLRNLLGIKNQGALDKVESTLSFLRAAELREHPVAGHFDLPHLLQIHARLFGDVYDWAGQVRS
VEIRKGHTVFARKLMIESAAGRLFDQLAGENHLRGLDPDQFSQRAGHYLGEINVLHPFREGNGRTQREFMGQLARQAGLR
IDWSAASQDEMVRASIDAYNGDSSGLSRLIRACLADPADRA
MKYAGDRGDPYLYSGTEVLRNLLGIKNQGALDKVESTLSFLRAAELREHPVAGHFDLPHLLQIHARLFGDVYDWAGQVRS
VEIRKGHTVFARKLMIESAAGRLFDQLAGENHLRGLDPDQFSQRAGHYLGEINVLHPFREGNGRTQREFMGQLARQAGLR
IDWSAASQDEMVRASIDAYNGDSSGLSRLIRACLADPADRA
Download Length: 606 bp
>T76003 NZ_CP021111:c4222756-4222151 [Bordetella genomosp. 13]
ATGAAATACGCAGGAGACCGCGGCGATCCGTACCTGTACAGCGGCACGGAGGTGTTGCGCAACCTGCTGGGCATCAAGAA
TCAGGGTGCGCTCGACAAGGTCGAGTCCACCCTTTCTTTTTTGCGCGCGGCCGAACTTCGCGAGCATCCGGTCGCGGGTC
ATTTCGACCTGCCGCACCTGCTGCAGATCCATGCCCGCCTGTTCGGCGACGTCTACGACTGGGCCGGCCAGGTGCGAAGC
GTGGAAATACGGAAAGGCCACACCGTGTTCGCCCGCAAGCTCATGATCGAAAGCGCGGCGGGCCGGCTGTTCGACCAACT
GGCCGGCGAGAACCATCTGCGCGGATTGGATCCCGACCAGTTCAGCCAGCGTGCCGGACACTATCTCGGCGAGATCAACG
TGCTGCATCCGTTCCGCGAAGGCAACGGCCGCACGCAGCGCGAATTCATGGGCCAGCTGGCGCGCCAGGCCGGGCTGCGC
ATCGACTGGAGTGCGGCTAGCCAGGACGAGATGGTGCGTGCCTCCATCGACGCGTACAACGGCGATTCCAGCGGACTATC
CCGCCTGATCCGCGCCTGCCTGGCCGACCCCGCGGACCGCGCCTAG
ATGAAATACGCAGGAGACCGCGGCGATCCGTACCTGTACAGCGGCACGGAGGTGTTGCGCAACCTGCTGGGCATCAAGAA
TCAGGGTGCGCTCGACAAGGTCGAGTCCACCCTTTCTTTTTTGCGCGCGGCCGAACTTCGCGAGCATCCGGTCGCGGGTC
ATTTCGACCTGCCGCACCTGCTGCAGATCCATGCCCGCCTGTTCGGCGACGTCTACGACTGGGCCGGCCAGGTGCGAAGC
GTGGAAATACGGAAAGGCCACACCGTGTTCGCCCGCAAGCTCATGATCGAAAGCGCGGCGGGCCGGCTGTTCGACCAACT
GGCCGGCGAGAACCATCTGCGCGGATTGGATCCCGACCAGTTCAGCCAGCGTGCCGGACACTATCTCGGCGAGATCAACG
TGCTGCATCCGTTCCGCGAAGGCAACGGCCGCACGCAGCGCGAATTCATGGGCCAGCTGGCGCGCCAGGCCGGGCTGCGC
ATCGACTGGAGTGCGGCTAGCCAGGACGAGATGGTGCGTGCCTCCATCGACGCGTACAACGGCGATTCCAGCGGACTATC
CCGCCTGATCCGCGCCTGCCTGGCCGACCCCGCGGACCGCGCCTAG
Antitoxin
Download Length: 63 a.a. Molecular weight: 6934.95 Da Isoelectric Point: 5.6664
>AT76003 WP_086081183.1 NZ_CP021111:c4222941-4222753 [Bordetella genomosp. 13]
MLAEHEHFERLAAVRSALASQRMEGLEPDPRAVADAERWARGEITIGAAVADFKMRVRLEMA
MLAEHEHFERLAAVRSALASQRMEGLEPDPRAVADAERWARGEITIGAAVADFKMRVRLEMA
Download Length: 189 bp
>AT76003 NZ_CP021111:c4222941-4222753 [Bordetella genomosp. 13]
CTGCTGGCCGAACACGAACACTTCGAGCGATTGGCAGCCGTGCGCAGCGCGCTGGCCAGCCAGCGCATGGAAGGGCTCGA
GCCCGATCCCCGGGCGGTGGCCGATGCCGAGCGCTGGGCGCGCGGCGAAATCACCATCGGCGCCGCCGTGGCCGATTTCA
AGATGCGAGTGCGCCTAGAAATGGCATGA
CTGCTGGCCGAACACGAACACTTCGAGCGATTGGCAGCCGTGCGCAGCGCGCTGGCCAGCCAGCGCATGGAAGGGCTCGA
GCCCGATCCCCGGGCGGTGGCCGATGCCGAGCGCTGGGCGCGCGGCGAAATCACCATCGGCGCCGCCGTGGCCGATTTCA
AGATGCGAGTGCGCCTAGAAATGGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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