Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1925164..1925809 Replicon chromosome
Accession NZ_CP021111
Organism Bordetella genomosp. 13 strain AU7206

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CAL15_RS08655 Protein ID WP_086078213.1
Coordinates 1925390..1925809 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CAL15_RS08650 Protein ID WP_086081003.1
Coordinates 1925164..1925403 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAL15_RS08625 1920189..1920536 + 348 WP_086078208.1 GFA family protein -
CAL15_RS08630 1920634..1920819 - 186 WP_086078209.1 YqaE/Pmp3 family membrane protein -
CAL15_RS08635 1920982..1921440 - 459 WP_198299181.1 GNAT family N-acetyltransferase -
CAL15_RS08640 1921672..1922331 + 660 WP_086078211.1 hypothetical protein -
CAL15_RS08645 1922445..1924655 - 2211 WP_086078212.1 hypothetical protein -
CAL15_RS08650 1925164..1925403 + 240 WP_086081003.1 DNA-binding protein Antitoxin
CAL15_RS08655 1925390..1925809 + 420 WP_086078213.1 type II toxin-antitoxin system VapC family toxin Toxin
CAL15_RS08660 1925847..1926596 - 750 WP_086078214.1 sulfite exporter TauE/SafE family protein -
CAL15_RS08665 1926735..1928021 - 1287 WP_086078215.1 benzoyl-CoA 2,3-epoxidase subunit BoxA -
CAL15_RS08670 1928076..1929503 - 1428 WP_086078216.1 benzoyl-CoA 2,3-epoxidase subunit BoxB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15686.82 Da        Isoelectric Point: 7.0746

>T76001 WP_086078213.1 NZ_CP021111:1925390-1925809 [Bordetella genomosp. 13]
MYLIDTNVISEARKGRRAHPGVRAFFRETAAADTPLYLSAITVGELRRGVDLLRHRGDDQQADRLDQWLTALLDQFARQV
LPVDHDVAVIWGRLRVPHPEHALDKLIAATALIHDLTVVTRNTSDYSGLGIRLRNPFDD

Download         Length: 420 bp

>T76001 NZ_CP021111:1925390-1925809 [Bordetella genomosp. 13]
ATGTATTTGATTGACACCAACGTCATCAGCGAGGCCCGGAAAGGAAGGCGTGCCCATCCGGGCGTACGGGCGTTCTTCCG
CGAGACCGCGGCGGCGGATACCCCGCTATACCTGTCCGCCATCACGGTCGGCGAATTGCGCCGCGGCGTCGACCTATTGC
GCCACCGTGGCGACGACCAGCAGGCCGACCGCCTGGACCAATGGCTGACGGCGCTGCTCGATCAGTTCGCCCGACAGGTA
CTTCCCGTGGACCATGACGTCGCGGTGATATGGGGCCGGCTGCGCGTACCCCATCCCGAACACGCGTTGGACAAGCTTAT
CGCCGCCACCGCGCTGATTCACGACCTTACCGTTGTCACGCGCAACACCAGCGACTATTCCGGCCTGGGCATCCGACTGC
GCAATCCGTTCGACGATTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8707.69 Da        Isoelectric Point: 5.6278

>AT76001 WP_086081003.1 NZ_CP021111:1925164-1925403 [Bordetella genomosp. 13]
MANLLVRGIDEALVQSLRERAAAHGRSAEAEHRDILARALRGPRRRSFAEVLASMPDVGHDADFARREDEAGAEPNVFD

Download         Length: 240 bp

>AT76001 NZ_CP021111:1925164-1925403 [Bordetella genomosp. 13]
ATGGCCAATCTACTTGTCCGTGGCATCGACGAAGCCCTGGTCCAAAGCCTGCGCGAACGCGCTGCCGCCCATGGGCGCAG
CGCCGAGGCGGAACATCGCGATATTCTCGCGCGTGCCTTGCGCGGCCCGCGGCGGCGCAGCTTCGCCGAAGTGTTGGCCT
CGATGCCTGATGTCGGCCATGACGCTGACTTCGCACGGCGCGAAGATGAAGCCGGGGCCGAGCCGAATGTATTTGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References