Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 327755..328304 Replicon chromosome
Accession NZ_CP021111
Organism Bordetella genomosp. 13 strain AU7206

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CAL15_RS01500 Protein ID WP_086077011.1
Coordinates 327755..328030 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CAL15_RS01505 Protein ID WP_086077012.1
Coordinates 328104..328304 (-) Length 67 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAL15_RS01485 324126..325100 - 975 WP_086077008.1 tripartite tricarboxylate transporter substrate binding protein -
CAL15_RS01490 325301..326443 - 1143 WP_086077009.1 mandelate racemase/muconate lactonizing enzyme family protein -
CAL15_RS01495 326676..327668 + 993 WP_086077010.1 LacI family DNA-binding transcriptional regulator -
CAL15_RS01500 327755..328030 - 276 WP_086077011.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CAL15_RS01505 328104..328304 - 201 WP_086077012.1 stability determinant Antitoxin
CAL15_RS01510 328438..329817 - 1380 WP_086077013.1 amidase -
CAL15_RS01515 329849..330784 - 936 WP_086080866.1 tripartite tricarboxylate transporter substrate binding protein -
CAL15_RS01520 330986..331867 + 882 WP_086077014.1 transcriptional regulator GcvA -
CAL15_RS01525 331901..332890 - 990 WP_086077015.1 tripartite tricarboxylate transporter substrate binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-90)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 92 a.a.        Molecular weight: 10338.83 Da        Isoelectric Point: 7.3991

>T75999 WP_086077011.1 NZ_CP021111:c328030-327755 [Bordetella genomosp. 13]
MLKISWRPTATDDLAEIVAFIAEHSVQAARTIRQRIESAVLPLAEHPYLYRSGRVPGTRELVAHPNYVVVYRVTDTAVEV
VNVLHSRQEYP

Download         Length: 276 bp

>T75999 NZ_CP021111:c328030-327755 [Bordetella genomosp. 13]
ATGCTGAAAATCTCCTGGCGTCCGACGGCCACCGATGACTTGGCGGAAATCGTCGCCTTTATTGCCGAGCACAGCGTGCA
GGCTGCACGTACCATCAGGCAGCGCATCGAAAGCGCCGTGCTGCCGCTGGCTGAACACCCGTACCTGTATCGCTCTGGCC
GCGTGCCGGGCACGCGAGAGCTCGTCGCGCATCCCAACTACGTTGTGGTCTACCGCGTCACCGACACAGCAGTCGAGGTA
GTCAACGTCTTGCACTCGCGCCAGGAATACCCCTGA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7412.27 Da        Isoelectric Point: 4.6982

>AT75999 WP_086077012.1 NZ_CP021111:c328304-328104 [Bordetella genomosp. 13]
MGAVLSPIVSEFETEEHAVSYDRWFRAKVQTSLADPRPSIPHDEVMARMDAIINAAEENRQQGQKG

Download         Length: 201 bp

>AT75999 NZ_CP021111:c328304-328104 [Bordetella genomosp. 13]
ATGGGCGCAGTCCTTTCTCCCATCGTCTCGGAGTTCGAGACTGAAGAACATGCGGTCAGCTATGACCGCTGGTTCCGCGC
GAAGGTACAAACCAGCCTGGCCGACCCACGCCCGAGCATTCCACATGACGAAGTGATGGCCCGCATGGATGCCATCATCA
ACGCCGCAGAAGAGAATCGTCAGCAGGGCCAAAAAGGCTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References