Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE(toxin) |
Location | 327755..328304 | Replicon | chromosome |
Accession | NZ_CP021111 | ||
Organism | Bordetella genomosp. 13 strain AU7206 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | CAL15_RS01500 | Protein ID | WP_086077011.1 |
Coordinates | 327755..328030 (-) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | CAL15_RS01505 | Protein ID | WP_086077012.1 |
Coordinates | 328104..328304 (-) | Length | 67 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CAL15_RS01485 | 324126..325100 | - | 975 | WP_086077008.1 | tripartite tricarboxylate transporter substrate binding protein | - |
CAL15_RS01490 | 325301..326443 | - | 1143 | WP_086077009.1 | mandelate racemase/muconate lactonizing enzyme family protein | - |
CAL15_RS01495 | 326676..327668 | + | 993 | WP_086077010.1 | LacI family DNA-binding transcriptional regulator | - |
CAL15_RS01500 | 327755..328030 | - | 276 | WP_086077011.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
CAL15_RS01505 | 328104..328304 | - | 201 | WP_086077012.1 | stability determinant | Antitoxin |
CAL15_RS01510 | 328438..329817 | - | 1380 | WP_086077013.1 | amidase | - |
CAL15_RS01515 | 329849..330784 | - | 936 | WP_086080866.1 | tripartite tricarboxylate transporter substrate binding protein | - |
CAL15_RS01520 | 330986..331867 | + | 882 | WP_086077014.1 | transcriptional regulator GcvA | - |
CAL15_RS01525 | 331901..332890 | - | 990 | WP_086077015.1 | tripartite tricarboxylate transporter substrate binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10338.83 Da Isoelectric Point: 7.3991
>T75999 WP_086077011.1 NZ_CP021111:c328030-327755 [Bordetella genomosp. 13]
MLKISWRPTATDDLAEIVAFIAEHSVQAARTIRQRIESAVLPLAEHPYLYRSGRVPGTRELVAHPNYVVVYRVTDTAVEV
VNVLHSRQEYP
MLKISWRPTATDDLAEIVAFIAEHSVQAARTIRQRIESAVLPLAEHPYLYRSGRVPGTRELVAHPNYVVVYRVTDTAVEV
VNVLHSRQEYP
Download Length: 276 bp
>T75999 NZ_CP021111:c328030-327755 [Bordetella genomosp. 13]
ATGCTGAAAATCTCCTGGCGTCCGACGGCCACCGATGACTTGGCGGAAATCGTCGCCTTTATTGCCGAGCACAGCGTGCA
GGCTGCACGTACCATCAGGCAGCGCATCGAAAGCGCCGTGCTGCCGCTGGCTGAACACCCGTACCTGTATCGCTCTGGCC
GCGTGCCGGGCACGCGAGAGCTCGTCGCGCATCCCAACTACGTTGTGGTCTACCGCGTCACCGACACAGCAGTCGAGGTA
GTCAACGTCTTGCACTCGCGCCAGGAATACCCCTGA
ATGCTGAAAATCTCCTGGCGTCCGACGGCCACCGATGACTTGGCGGAAATCGTCGCCTTTATTGCCGAGCACAGCGTGCA
GGCTGCACGTACCATCAGGCAGCGCATCGAAAGCGCCGTGCTGCCGCTGGCTGAACACCCGTACCTGTATCGCTCTGGCC
GCGTGCCGGGCACGCGAGAGCTCGTCGCGCATCCCAACTACGTTGTGGTCTACCGCGTCACCGACACAGCAGTCGAGGTA
GTCAACGTCTTGCACTCGCGCCAGGAATACCCCTGA
Antitoxin
Download Length: 67 a.a. Molecular weight: 7412.27 Da Isoelectric Point: 4.6982
>AT75999 WP_086077012.1 NZ_CP021111:c328304-328104 [Bordetella genomosp. 13]
MGAVLSPIVSEFETEEHAVSYDRWFRAKVQTSLADPRPSIPHDEVMARMDAIINAAEENRQQGQKG
MGAVLSPIVSEFETEEHAVSYDRWFRAKVQTSLADPRPSIPHDEVMARMDAIINAAEENRQQGQKG
Download Length: 201 bp
>AT75999 NZ_CP021111:c328304-328104 [Bordetella genomosp. 13]
ATGGGCGCAGTCCTTTCTCCCATCGTCTCGGAGTTCGAGACTGAAGAACATGCGGTCAGCTATGACCGCTGGTTCCGCGC
GAAGGTACAAACCAGCCTGGCCGACCCACGCCCGAGCATTCCACATGACGAAGTGATGGCCCGCATGGATGCCATCATCA
ACGCCGCAGAAGAGAATCGTCAGCAGGGCCAAAAAGGCTAA
ATGGGCGCAGTCCTTTCTCCCATCGTCTCGGAGTTCGAGACTGAAGAACATGCGGTCAGCTATGACCGCTGGTTCCGCGC
GAAGGTACAAACCAGCCTGGCCGACCCACGCCCGAGCATTCCACATGACGAAGTGATGGCCCGCATGGATGCCATCATCA
ACGCCGCAGAAGAGAATCGTCAGCAGGGCCAAAAAGGCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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